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AlphaFold monomer V2.0 prediction for nucleolar complex-associated protein 3 (Q07896)

Analyse AlphaFold monomer V2.0 prediction for nucleolar complex-associated protein 3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q07896
Type
protein
Length
663 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9073C46348542FfE4327c3F363F9B51B22058e75
Molecule
Nucleolar complex-associated protein 3
UniProt
Q07896
Pockets
7 · best druggability 0.51

Structure

1 distinct chain · 58% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleolar complex-associated protein 3protein66358% helix, 2% strandQ07896

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12500.510.7528empty
21170.490.8014empty
31760.470.7624empty
41890.440.7432empty
51030.440.7816empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 7NAC · State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model · an experimental structure of the same protein · chain A against I, TM-score 0.64
  • 7R7A · State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model · an experimental structure of the same protein · chain A against I, TM-score 0.64
  • 8V87 · 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) · an experimental structure of the same protein · chain A against I, TM-score 0.64
  • 7R6K · State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region · an experimental structure of the same protein · chain A against I, TM-score 0.63
  • 6EM5 · State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of… · an experimental structure of the same protein · chain A against I, TM-score 0.56
  • 6EM5 · State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of… · an experimental structure of the same protein · chain A against I, TM-score 0.56
  • 6ELZ · State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S… · an experimental structure of the same protein · chain A against I, TM-score 0.54
  • 7OHR · Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae · an experimental structure of the same protein · chain A against I, TM-score 0.52
  • 7R72 · State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model · an experimental structure of the same protein · chain A against I, TM-score 0.44

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