Research workbench
AlphaFold monomer V2.0 prediction for nacht, lrr and pyd domains- containing protein 1 (Q9C000)
Analyse AlphaFold monomer V2.0 prediction for nacht, lrr and pyd domains- containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9C000
- Type
- protein
- Length
- 1,473 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35612D34a32C306CA4fc1edA9360D1F717e25950
- Molecule
- Nacht, lrr and pyd domains-containing protein 1
- UniProt
- Q9C000
- Pockets
- 20 · best druggability 0.87
Structure
1 distinct chain · 31% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nacht, lrr and pyd domains-containing protein 1 | protein | 1473 | 31% helix, 15% strand | Q9C000 |
Pockets
20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1030 | 0.87 | 0.88 | 101 | empty |
| 2 | 1032 | 0.80 | 0.82 | 82 | empty |
| 3 | 1063 | 0.78 | 0.80 | 94 | empty |
| 4 | 169 | 0.63 | 0.84 | 18 | empty |
| 5 | 325 | 0.59 | 0.76 | 37 | empty |
Compared structures
- 7WGE · Human NLRP1 complexed with thioredoxin · an experimental structure of the same protein · chain A against A, TM-score 0.38
- 5Y3S · Crystal structure of human NLRP1 leucine rich repeat domain · an experimental structure of the same protein · chain A against D, TM-score 0.13
- 5Y3S · Crystal structure of human NLRP1 leucine rich repeat domain · an experimental structure of the same protein · chain A against D, TM-score 0.13
- 4IM6 · Lrr domain from human NLRP1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 4IM6 · LRR domain from human NLRP1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 8ZGD · The Crystal Structure of the NLRP1_LRR domain from Biortus. · an experimental structure of the same protein · chain A against A, TM-score 0.13
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9C000
- Elsewhere: UniProt Q9C000 · AlphaFold DB Q9C000
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