UniProt Q9C000
NACHT, LRR and PYD domains-containing protein 1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (UniProt Q9C000): 19 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 41 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9C000
- Protein
- NACHT, LRR and PYD domains-containing protein 1
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 41 · 4 records with a druggable one
Structures
20 records of Q9C000 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PN5 | NMR structure of the NALP1 Pyrin domain (PYD) | solution nmr | A | — | — |
| 1PN5 | NMR structure of the NALP1 pyrin domain (pyd) | solution nmr | A | — | — |
| 3KAT | Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics… | x-ray diffraction | A | — | — |
| 3KAT | Crystal structure of the card domain of the human NLRP1 protein, northeast structural genomics… | x-ray diffraction | A | — | — |
| 4IFP | X-ray Crystal Structure of Human NLRP1 CARD Domain | x-ray diffraction | A, B, C | — | — |
| 4IFP | X-ray crystal structure of human NLRP1 card domain | x-ray diffraction | A, B, C | — | — |
| 4IM6 | LRR domain from human NLRP1 | x-ray diffraction | A | — | — |
| 4IM6 | Lrr domain from human NLRP1 | x-ray diffraction | A | — | — |
| 5Y3S | Crystal structure of human NLRP1 leucine rich repeat domain | x-ray diffraction | A, B, C, D | PO4, NA | — |
| 5Y3S | Crystal structure of human NLRP1 leucine rich repeat domain | x-ray diffraction | A, B, C, D | PO4, NA | — |
| 6K7V | Structure of NLRP1 CARD filament | electron microscopy | J, A, B, C, D, E, F, G, H, I, K, L | — | — |
| 6K7V | Structure of NLRP1 card filament | electron microscopy | J, A, B, C, D, E, F, G, H, I, K, L | — | — |
| 6X6A | Cryo-EM structure of NLRP1-DPP9 complex | electron microscopy | B, G, C, E, I, F | — | 14 (best 0.85) |
| 6X6A | Cryo-EM structure of NLRP1-DPP9 complex | electron microscopy | B, G, C, E, I, F | — | — |
| 6X6C | Cryo-EM structure of NLRP1-DPP9-VbP complex | electron microscopy | E, F | — | 6 (best 0.70) |
| 6X6C | Cryo-EM structure of NLRP1-DPP9-vbp complex | electron microscopy | E, F | — | — |
| 6XKK | Cryo-EM structure of the NLRP1-CARD filament | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v | — | — |
| 6XKK | Cryo-EM structure of the NLRP1-card filament | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v | — | — |
| 8ZGD | The Crystal Structure of the NLRP1_LRR domain from Biortus. | x-ray diffraction | A | — | 1 (best 0.56) |
| Q9C000 | AlphaFold monomer V2.0 prediction for nacht, lrr and pyd domains- containing protein 1 (Q9C000) | predicted | A | — | 20 (best 0.87) |
Ligands
Experiment against prediction
- 5Y3S chain D against the predicted model Q9C000: TM-score 0.98, RMSD 0.82 Å
- 5Y3S chain D against the predicted model Q9C000: TM-score 0.98, RMSD 0.82 Å
- 6XKK chain A against the predicted model Q9C000: TM-score 0.98, RMSD 0.48 Å
- 6XKK chain A against the predicted model Q9C000: TM-score 0.98, RMSD 0.48 Å
- 5Y3S chain B against the predicted model Q9C000: TM-score 0.98, RMSD 1.00 Å
- 5Y3S chain B against the predicted model Q9C000: TM-score 0.98, RMSD 1.00 Å
- 5Y3S chain A against the predicted model Q9C000: TM-score 0.97, RMSD 1.02 Å
- 5Y3S chain A against the predicted model Q9C000: TM-score 0.97, RMSD 1.02 Å
- 4IM6 chain A against the predicted model Q9C000: TM-score 0.97, RMSD 1.05 Å
- 4IM6 chain A against the predicted model Q9C000: TM-score 0.97, RMSD 1.05 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.