Research workbench
AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 2 (Q13469)
Analyse AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q13469
- Type
- protein
- Length
- 925 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x72bB5e004C63E96c37EcA6C9EafAe518f04aEe94
- Molecule
- Nuclear factor of activated T-cells, cytoplasmic 2
- UniProt
- Q13469
- Pockets
- 2 · best druggability 0.41
Structure
1 distinct chain · 4% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear factor of activated T-cells, cytoplasmic 2 | protein | 925 | 4% helix, 14% strand | Q13469 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.41 | 0.77 | 18 | empty |
| 2 | 65 | 0.29 | 0.73 | 15 | empty |
Compared structures
- 2O93 · Crystal structure of nfat bound to the HIV-1 ltr tandem kappab enhancer element · an experimental structure of the same protein · chain A against M, TM-score 0.28
- 2O93 · Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element · an experimental structure of the same protein · chain A against M, TM-score 0.28
- 1PZU · An asymmetric NFAT1-rhr homodimer on a pseudo-palindromic, kappa-B site · an experimental structure of the same protein · chain A against B, TM-score 0.25
- 1PZU · An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site · an experimental structure of the same protein · chain A against B, TM-score 0.25
- 8OW4 · 2.75 angstrom crystal structure of human NFAT1 with bound DNA · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 1P7H · Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element · an experimental structure of the same protein · chain A against L, TM-score 0.22
- 1P7H · Structure of NFAT1 bound as a dimer to the HIV-1 ltr kb element · an experimental structure of the same protein · chain A against L, TM-score 0.22
- 1OWR · Crystal structure of human NFAT1 bound monomerically to DNA · an experimental structure of the same protein · chain A against M, TM-score 0.22
- 1OWR · Crystal structure of human NFAT1 bound monomerically to DNA · an experimental structure of the same protein · chain A against M, TM-score 0.22
- 3QRF · Structure of a domain-swapped FOXP3 dimer · an experimental structure of the same protein · chain A against N, TM-score 0.21
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13469
- Elsewhere: UniProt Q13469 · AlphaFold DB Q13469
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