Research workbench
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (Q9D6J6)
Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9D6J6
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8af20c751cd561e3F0B6141F3317c17894026A1c
- Molecule
- NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
- UniProt
- Q9D6J6
- Pockets
- 3 · best druggability 0.59
Structure
1 distinct chain · 31% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | protein | 248 | 31% helix, 10% strand | Q9D6J6 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 336 | 0.59 | 0.78 | 38 | empty |
| 2 | 123 | 0.49 | 0.79 | 21 | empty |
| 3 | 131 | 0.35 | 0.72 | 19 | empty |
Compared structures
- 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7B93 · Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at… · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8OM1 · Mitochondrial complex I from Mus musculus in the active state · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8RGT · Open Complex I from murine brain · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8RGQ · Open Complex I from murine liver · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8PW5 · CS respirasome from murine liver · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8OLT · Mitochondrial complex I from Mus musculus in the active state bound with piericidin A · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8PW7 · A respirasome from murine liver · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 8RGP · Closed Complex I from murine brain · an experimental structure of the same protein · chain A against 2, TM-score 0.85
- 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against E, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9D6J6
- Elsewhere: UniProt Q9D6J6 · AlphaFold DB Q9D6J6
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