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AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (P19404)

Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P19404
Type
protein
Length
249 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
Molecule
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
UniProt
P19404
Pockets
3 · best druggability 0.64

Structure

1 distinct chain · 32% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialprotein24932% helix, 10% strandP19404

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14290.640.7853empty
21240.500.8021empty
3510.250.7313empty

Compared structures

  • 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against O, TM-score 0.81
  • 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against O, TM-score 0.81
  • 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against BO, TM-score 0.81
  • 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against O, TM-score 0.81
  • 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against O, TM-score 0.81
  • 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against O, TM-score 0.81

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