UniProt P19404
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (P19404)
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (UniProt P19404), EC 1.6.5.3, 1.6.99.3: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and…
- UniProt
- P19404
- Protein
- NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
- EC
- 1.6.5.3, 1.6.99.3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 3 records with a druggable one
Structures
7 records of P19404 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | O | FES | 4 (best 0.77) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | O | FES | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | O | FES | 1 (best 0.81) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | O | FES | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | O | FES | — |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | O, BO | FES | — |
| P19404 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial… | predicted | A | — | 3 (best 0.64) |
Ligands
- FES · Fe2/s2 (inorganic) cluster · in 6 records
Experiment against prediction
- 5XTD chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTD chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTH chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTI chain BO against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTI chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTB chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
- 5XTB chain O against the predicted model P19404: TM-score 0.94, RMSD 1.29 Å
Elsewhere
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