Research workbench
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (P04394)
Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P04394
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
- UniProt
- P04394
- Pockets
- 2 · best druggability 0.61
Structure
1 distinct chain · 32% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | protein | 249 | 32% helix, 10% strand | P04394 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 326 | 0.61 | 0.79 | 42 | empty |
| 2 | 137 | 0.48 | 0.78 | 23 | empty |
Compared structures
- 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSK · Bovine complex I in lipid nanodisc, Active-Q10 · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSO · Bovine complex I in lipid nanodisc, State 3 (Slack) · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSO · Bovine complex I in lipid nanodisc, state 3 (slack) · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSN · Bovine complex I in lipid nanodisc, deactive-apo · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 7QSN · Bovine complex I in lipid nanodisc, Deactive-apo · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8Q46 · Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8Q45 · Inward-facing, closed proteoliposome complex I at 2.7 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8Q47 · Inward-facing, open1 proteoliposome complex I at 2.9 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against E, TM-score 0.85
- 8Q49 · Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against E, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04394
- Elsewhere: UniProt P04394 · AlphaFold DB P04394
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