Research workbench
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Q91YT0)
Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q91YT0
- Type
- protein
- Length
- 464 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x731d8ea2236F13759e0bE3C1C2bA23586AF10363
- Molecule
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- UniProt
- Q91YT0
- Pockets
- 2 · best druggability 0.75
Structure
1 distinct chain · 45% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | protein | 464 | 45% helix, 13% strand | Q91YT0 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 560 | 0.75 | 0.83 | 59 | empty |
| 2 | 55 | 0.27 | 0.73 | 14 | empty |
Compared structures
- 8OM1 · Mitochondrial complex I from Mus musculus in the active state · an experimental structure of the same protein · chain A against F, TM-score 0.93
- 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against 1, TM-score 0.93
- 8RGT · Open Complex I from murine brain · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 8RGQ · Open Complex I from murine liver · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 8RGP · Closed Complex I from murine brain · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 8PW5 · CS respirasome from murine liver · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 8OLT · Mitochondrial complex I from Mus musculus in the active state bound with piericidin A · an experimental structure of the same protein · chain A against F, TM-score 0.92
- 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 8PW7 · A respirasome from murine liver · an experimental structure of the same protein · chain A against 1, TM-score 0.92
- 7B93 · Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at… · an experimental structure of the same protein · chain A against F, TM-score 0.92
- 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against F, TM-score 0.92
- 8CA4 · Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain). · an experimental structure of the same protein · chain A against F, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91YT0
- Elsewhere: UniProt Q91YT0 · AlphaFold DB Q91YT0
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