Research workbench
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (P49821)
Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P49821
- Type
- protein
- Length
- 464 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb92D3b0E198eC4a6c8dCd4D0aFDD2FC07B271c2C
- Molecule
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- UniProt
- P49821
- Pockets
- 3 · best druggability 0.76
Structure
1 distinct chain · 45% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | protein | 464 | 45% helix, 13% strand | P49821 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 511 | 0.76 | 0.84 | 52 | empty |
| 2 | 52 | 0.27 | 0.74 | 13 | empty |
| 3 | 69 | 0.27 | 0.72 | 15 | empty |
Compared structures
- 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49821
- Elsewhere: UniProt P49821 · AlphaFold DB P49821
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