UniProt P49821
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (P49821)
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (UniProt P49821), EC 1.6.5.3, 1.6.99.3: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and…
- UniProt
- P49821
- Protein
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- EC
- 1.6.5.3, 1.6.99.3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 3 records with a druggable one
Structures
7 records of P49821 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | A | SF4, FMN | 5 (best 0.78) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | A | SF4, FMN | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | A | SF4, FMN | 1 (best 0.81) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | A | SF4, FMN | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | A | SF4, FMN | — |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | A, BA | SF4, FMN | — |
| P49821 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial… | predicted | A | — | 3 (best 0.76) |
Ligands
Experiment against prediction
- 5XTI chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTD chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTH chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTD chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTB chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTI chain BA against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
- 5XTB chain A against the predicted model P49821: TM-score 0.98, RMSD 1.08 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.