Research workbench
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (P28331)
Analyse AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase 75 kda… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P28331
- Type
- protein
- Length
- 727 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- NADH-ubiquinone oxidoreductase 75 kda subunit, mitochondrial
- UniProt
- P28331
- Pockets
- 7 · best druggability 0.62
Structure
1 distinct chain · 32% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase 75 kda subunit, mitochondrial | protein | 727 | 32% helix, 17% strand | P28331 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 354 | 0.62 | 0.78 | 37 | empty |
| 2 | 183 | 0.57 | 0.81 | 38 | empty |
| 3 | 178 | 0.49 | 0.76 | 26 | empty |
| 4 | 112 | 0.45 | 0.79 | 29 | empty |
| 5 | 91 | 0.35 | 0.75 | 20 | empty |
Compared structures
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against M, TM-score 0.93
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against M, TM-score 0.93
- 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against M, TM-score 0.93
- 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against M, TM-score 0.93
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against M, TM-score 0.93
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against M, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28331
- Elsewhere: UniProt P28331 · AlphaFold DB P28331
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