UniProt P28331
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (P28331)
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (UniProt P28331), EC 1.6.5.3, 1.6.99.3: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and…
- UniProt
- P28331
- Protein
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- EC
- 1.6.5.3, 1.6.99.3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 5 records with a druggable one
Structures
7 records of P28331 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | M | SF4, FES | 12 (best 0.89) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | M | SF4, FES | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | M | SF4, FES | 4 (best 0.86) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | M | SF4, FES | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | M | SF4, FES | 3 (best 0.89) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | M, BM | SF4, FES | 2 (best 0.89) |
| P28331 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase 75 kda subunit, mitochondrial… | predicted | A | — | 7 (best 0.62) |
Ligands
Experiment against prediction
- 5XTB chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTB chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTH chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTI chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTD chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTD chain M against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
- 5XTI chain BM against the predicted model P28331: TM-score 0.98, RMSD 1.17 Å
Elsewhere
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