AlphaFold monomer V2.0 prediction for kinetochore protein NDC80 (P40460)

Structure

1 distinct chain · 71% helix, 0% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8G0Q · Crystal structure of the yeast Ndc80:Nuf2 head region with a bound Dam1 segment · an experimental structure of the same protein · chain A against C, TM-score 0.36
• 8V11 · Structure of a Saccharomyces cerevisiae Ipl1 peptide Bound to dwarf Ndc80 complex · an experimental structure of the same protein · chain A against E, TM-score 0.36
• 8V10 · Structure of a Saccharomyces cerevisiae Mps1 peptide bound to dwarf Ndc80 Complex · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 5TCS · Crystal structure of a dwarf NDC80 tetramer · an experimental structure of the same protein · chain A against A, TM-score 0.34
• 8QAU · Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex · an experimental structure of the same protein · chain A against A, TM-score 0.32
• 5TD8 · Crystal structure of an extended dwarf NDC80 complex · an experimental structure of the same protein · chain A against A, TM-score 0.29
• 5TD8 · Crystal structure of an Extended Dwarf Ndc80 Complex · an experimental structure of the same protein · chain A against A, TM-score 0.29
• 8Q84 · Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex · an experimental structure of the same protein · chain A against F, TM-score 0.25
• 8Q85 · Outer kinetochore Dam1 protomer monomer Ndc80-Nuf2 coiled-coil complex · an experimental structure of the same protein · chain A against F, TM-score 0.24

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P40460
• Elsewhere: UniProt P40460 · AlphaFold DB P40460