UniProt P40460
Kinetochore protein NDC80 (P40460)
Kinetochore protein NDC80 (UniProt P40460): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40460
- Protein
- Kinetochore protein NDC80
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 29 · 3 records with a druggable one
Structures
6 records of P40460 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TCS | Crystal structure of a dwarf NDC80 tetramer | x-ray diffraction | A | — | — |
| 5TD8 | Crystal structure of an Extended Dwarf Ndc80 Complex | x-ray diffraction | A | HG | 9 (best 0.73) |
| 5TD8 | Crystal structure of an extended dwarf NDC80 complex | x-ray diffraction | A | HG | — |
| 8Q84 | Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex | electron microscopy | A, F | — | 2 (best 0.68) |
| 8V11 | Structure of a Saccharomyces cerevisiae Ipl1 peptide Bound to dwarf Ndc80 complex | x-ray diffraction | A, E | — | 16 (best 0.76) |
| P40460 | AlphaFold monomer V2.0 prediction for kinetochore protein NDC80 (P40460) | predicted | A | — | 2 (best 0.42) |
Ligands
- HG · Mercury (II) ion · in 2 records
Experiment against prediction
- 8V11 chain E against the predicted model P40460: TM-score 0.85, RMSD 2.84 Å
- 5TCS chain A against the predicted model P40460: TM-score 0.85, RMSD 2.51 Å
- 8V11 chain A against the predicted model P40460: TM-score 0.80, RMSD 3.16 Å
- 5TD8 chain A against the predicted model P40460: TM-score 0.68, RMSD 4.11 Å
- 5TD8 chain A against the predicted model P40460: TM-score 0.68, RMSD 4.11 Å
- 8Q84 chain F against the predicted model P40460: TM-score 0.54, RMSD 3.90 Å
- 8Q84 chain A against the predicted model P40460: TM-score 0.53, RMSD 3.92 Å
Elsewhere
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