Research workbench
AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 2 (Q9WUI9)
Analyse AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 2 (Q9WUI9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9WUI9
- Type
- protein
- Length
- 1,465 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Nuclear receptor coactivator 2
- UniProt
- Q9WUI9
- Pockets
- 3 · best druggability 0.45
Structure
1 distinct chain · 15% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear receptor coactivator 2 | protein | 1465 | 15% helix, 6% strand | Q9WUI9 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.45 | 0.75 | 31 | empty |
| 2 | 101 | 0.43 | 0.78 | 19 | empty |
| 3 | 52 | 0.35 | 0.78 | 11 | empty |
Compared structures
- 1XLS · Crystal structure of the mouse CAR/RXR LBD heterodimer bound to TCPOBOP and 9cRA and a… · an experimental structure of the same protein · chain A against M, TM-score 0.01
- 1XLS · Crystal structure of the mouse CAR/RXR lbd heterodimer bound to tcpobop and 9CRA and a… · an experimental structure of the same protein · chain A against M, TM-score 0.01
- 3HM1 · Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with… · an experimental structure of the same protein · chain A against C, TM-score 0.01
- 3HM1 · Crystal structure of human estrogen receptor alpha ligand-binding domain in complex with… · an experimental structure of the same protein · chain A against C, TM-score 0.01
- 3HLV · Crystal structure of human estrogen receptor alpha ligand-binding domain in complex with… · an experimental structure of the same protein · chain A against C, TM-score 0.01
- 3HLV · Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with… · an experimental structure of the same protein · chain A against C, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WUI9
- Elsewhere: UniProt Q9WUI9 · AlphaFold DB Q9WUI9
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