UniProt Q9WUI9
Nuclear receptor coactivator 2 (Q9WUI9)
Nuclear receptor coactivator 2 (UniProt Q9WUI9): 6 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9WUI9
- Protein
- Nuclear receptor coactivator 2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
7 records of Q9WUI9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XLS | Crystal structure of the mouse CAR/RXR LBD heterodimer bound to TCPOBOP and 9cRA and a TIF2 peptide… | x-ray diffraction | I, J, K, L, M, N, O, P | — | — |
| 1XLS | Crystal structure of the mouse CAR/RXR lbd heterodimer bound to tcpobop and 9CRA and a TIF2 peptide… | x-ray diffraction | I, J, K, L, M, N, O, P | — | — |
| 3HLV | Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a… | x-ray diffraction | C, D | — | — |
| 3HLV | Crystal structure of human estrogen receptor alpha ligand-binding domain in complex with a… | x-ray diffraction | C, D | — | — |
| 3HM1 | Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a… | x-ray diffraction | C, D | — | — |
| 3HM1 | Crystal structure of human estrogen receptor alpha ligand-binding domain in complex with a… | x-ray diffraction | C, D | — | — |
| Q9WUI9 | AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 2 (Q9WUI9) | predicted | A | — | 3 (best 0.45) |
Experiment against prediction
- 3HM1 chain D against the predicted model Q9WUI9: TM-score 0.84, RMSD 0.29 Å
- 3HM1 chain D against the predicted model Q9WUI9: TM-score 0.84, RMSD 0.29 Å
- 3HLV chain C against the predicted model Q9WUI9: TM-score 0.82, RMSD 0.27 Å
- 3HLV chain C against the predicted model Q9WUI9: TM-score 0.82, RMSD 0.27 Å
- 3HM1 chain C against the predicted model Q9WUI9: TM-score 0.79, RMSD 0.28 Å
- 3HM1 chain C against the predicted model Q9WUI9: TM-score 0.79, RMSD 0.28 Å
- 3HLV chain D against the predicted model Q9WUI9: TM-score 0.70, RMSD 0.19 Å
- 3HLV chain D against the predicted model Q9WUI9: TM-score 0.70, RMSD 0.19 Å
- 1XLS chain I against the predicted model Q9WUI9: TM-score 0.42, RMSD 1.98 Å
- 1XLS chain I against the predicted model Q9WUI9: TM-score 0.42, RMSD 1.98 Å
Elsewhere
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