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AlphaFold monomer V2.0 prediction for myosin light chain 1/3, skeletal muscle isoform (P05977)

Analyse AlphaFold monomer V2.0 prediction for myosin light chain 1/3, skeletal muscle… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P05977
Type
protein
Length
188 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
Molecule
Myosin light chain 1/3, skeletal muscle isoform
UniProt
P05977
Pockets
1 · best druggability 0.50

Structure

1 distinct chain · 46% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMyosin light chain 1/3, skeletal muscle isoformprotein18846% helix, 7% strandP05977

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12860.500.7323empty

Compared structures

  • 8EFE · Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain · an experimental structure of the same protein · chain A against B, TM-score 0.73
  • 8EFD · Human cardiac myosin II and associated essential light chain in the rigor conformation · an experimental structure of the same protein · chain A against B, TM-score 0.72
  • 7QIO · Homology model of myosin neck domain in skeletal sarcomere · an experimental structure of the same protein · chain A against N, TM-score 0.72
  • 7QIO · Homology model of myosin neck domain in skeletal sarcomere · an experimental structure of the same protein · chain A against N, TM-score 0.72
  • 7NEP · Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle… · an experimental structure of the same protein · chain A against N, TM-score 0.71
  • 7NEP · Homology model of the in situ actomyosin complex from the a-band of mouse psoas muscle… · an experimental structure of the same protein · chain A against N, TM-score 0.71

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