UniProt P05977

Myosin light chain 1/3, skeletal muscle isoform (P05977)

Myosin light chain 1/3, skeletal muscle isoform (UniProt P05977): 5 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P05977
Protein: Myosin light chain 1/3, skeletal muscle isoform
Experimental structures: 5
Predicted models: 1
Pockets: 6 · 4 records with a druggable one

Structures

6 records of P05977 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7NEP	Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle sarcomere in…	electron microscopy	N, O	—	1 (best 0.74)
7NEP	Homology model of the in situ actomyosin complex from the a-band of mouse psoas muscle sarcomere in…	electron microscopy	N, O	—	—
7QIO	Homology model of myosin neck domain in skeletal sarcomere	electron microscopy	N, O	—	—
8EFD	Human cardiac myosin II and associated essential light chain in the rigor conformation	electron microscopy	B	—	2 (best 0.75)
8EFE	Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain	electron microscopy	B	—	2 (best 0.76)
P05977	AlphaFold monomer V2.0 prediction for myosin light chain 1/3, skeletal muscle isoform (P05977)	predicted	A	—	1 (best 0.50)

Experiment against prediction

8EFE chain B against the predicted model P05977: TM-score 0.93, RMSD 1.25 Å
8EFD chain B against the predicted model P05977: TM-score 0.91, RMSD 1.47 Å
7QIO chain N against the predicted model P05977: TM-score 0.90, RMSD 1.75 Å
7NEP chain N against the predicted model P05977: TM-score 0.89, RMSD 1.96 Å
7NEP chain N against the predicted model P05977: TM-score 0.89, RMSD 1.96 Å
7NEP chain O against the predicted model P05977: TM-score 0.89, RMSD 1.86 Å

Elsewhere

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