AlphaFold monomer V2.0 prediction for adenine DNA glycosylase (P83847)

Structure

1 distinct chain · 47% helix, 14% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 4YPR · Crystal structure of D144N muty bound to its anti-substrate · an experimental structure of the same protein · chain A against A, TM-score 0.96
• 4YPR · Crystal Structure of D144N MutY bound to its anti-substrate · an experimental structure of the same protein · chain A against A, TM-score 0.96
• 6U7T · Muty adenine glycosylase bound to DNA containing a transition state analog (1N) paired… · an experimental structure of the same protein · chain A against A, TM-score 0.95
• 6Q0C · Muty adenine glycosylase bound to DNA containing a transition state analog (1N) paired… · an experimental structure of the same protein · chain A against A, TM-score 0.95
• 8DWF · Glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with… · an experimental structure of the same protein · chain A against A, TM-score 0.95
• 1VRL · MutY adenine glycosylase in complex with DNA and soaked adenine free base · an experimental structure of the same protein · chain A against A, TM-score 0.94
• 1VRL · Muty adenine glycosylase in complex with DNA and soaked adenine free base · an experimental structure of the same protein · chain A against A, TM-score 0.94
• 8DWD · Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired… · an experimental structure of the same protein · chain A against A, TM-score 0.93
• 1RRS · MutY adenine glycosylase in complex with DNA containing an abasic site · an experimental structure of the same protein · chain A against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P83847
• Elsewhere: UniProt P83847 · AlphaFold DB P83847