Research workbench
AlphaFold monomer V2.0 prediction for adenine DNA glycosylase (Q9UIF7)
Analyse AlphaFold monomer V2.0 prediction for adenine DNA glycosylase (Q9UIF7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9UIF7
- Type
- protein
- Length
- 546 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Adenine DNA glycosylase
- UniProt
- Q9UIF7
- Pockets
- 4 · best druggability 0.57
Structure
1 distinct chain · 37% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenine DNA glycosylase | protein | 546 | 37% helix, 10% strand | Q9UIF7 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.57 | 0.81 | 23 | empty |
| 2 | 135 | 0.43 | 0.76 | 23 | empty |
| 3 | 97 | 0.31 | 0.72 | 22 | empty |
| 4 | 59 | 0.30 | 0.75 | 15 | empty |
Compared structures
- 8FAY · Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N)… · an experimental structure of the same protein · chain A against D, TM-score 0.70
- 3N5N · Crystal structure analysis of the catalytic domain and interdomain connector of human… · an experimental structure of the same protein · chain A against Y, TM-score 0.44
- 3N5N · Crystal structure analysis of the catalytic domain and interdomain connector of human… · an experimental structure of the same protein · chain A against Y, TM-score 0.44
- 1X51 · Solution structure of the NUDIX domain from human A/G-specific adenine DNA glycosylase… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 1X51 · Solution structure of the nudix domain from human A/G-specific adenine DNA glycosylase… · an experimental structure of the same protein · chain A against A, TM-score 0.25
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UIF7
- Elsewhere: UniProt Q9UIF7 · AlphaFold DB Q9UIF7
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