MolNFT v1 · #26950 · protein
Solution structure of the nudix domain from human A/G-specific adenine DNA glycosylase alpha-3 splice isoform
1X51: “Solution structure of the nudix domain from human A/G-specific adenine DNA glycosylase alpha-3 splice isoform”. Solution nmr, 2 pockets (best druggability 0.55). MolNFT v1 #26950 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1X51
- Type
- protein
- Length
- 155 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- A/G-specific adenine DNA glycosylase
- EC
- 3.2.2.-
- UniProt
- Q9UIF7
- Pockets
- 2 · best druggability 0.55
Structure
solution nmr · 1 distinct chain · 21% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | A/G-specific adenine DNA glycosylase (EC 3.2.2.-) | protein | 155 | 21% helix, 28% strand | Q9UIF7 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 283 | 0.55 | 0.76 | 35 | empty |
| 2 | 114 | 0.39 | 0.75 | 18 | empty |
Compared structures
- 1X51 · Solution structure of the NUDIX domain from human A/G-specific adenine DNA glycosylase… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UIF7 · AlphaFold monomer V2.0 prediction for adenine DNA glycosylase (Q9UIF7) · a predicted model of the same protein · chain A against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UIF7
- Elsewhere: RCSB PDB 1X51 · PDBe 1X51 · UniProt Q9UIF7
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