Research workbench
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (O67518)
Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (O67518) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O67518
- Type
- protein
- Length
- 425 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- DNA mismatch repair protein mutl
- UniProt
- O67518
- Pockets
- 3 · best druggability 0.76
Structure
1 distinct chain · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein mutl | protein | 425 | 32% helix, 26% strand | O67518 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 754 | 0.76 | 0.81 | 67 | empty |
| 2 | 68 | 0.36 | 0.77 | 16 | empty |
| 3 | 61 | 0.34 | 0.77 | 15 | empty |
Compared structures
- 6LZK · Aquifex aeolicus mutl ATPase domain with K252N mutation · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 6LZK · Aquifex aeolicus MutL ATPase domain with K252N mutation · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 5X9Y · Crystal structure of the ATPase domain from bacterial mismatch repair endonuclease… · an experimental structure of the same protein · chain A against C, TM-score 0.57
- 5X9Y · Crystal structure of the ATPase domain from bacterial mismatch repair endonuclease… · an experimental structure of the same protein · chain A against C, TM-score 0.57
- 6LZJ · Aquifex aeolicus mutl ATPase domain complexed with amppcp · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 6LZJ · Aquifex aeolicus MutL ATPase domain complexed with AMPPCP · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 6LZI · Aquifex aeolicus MutL ATPase domain complexed with ADP · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 6LZI · Aquifex aeolicus mutl ATPase domain complexed with ADP · an experimental structure of the same protein · chain A against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67518
- Elsewhere: UniProt O67518 · AlphaFold DB O67518
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