Research workbench
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase msl-2 (P50534)
Analyse AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase msl-2 (P50534) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P50534
- Type
- protein
- Length
- 773 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB05a6C07895e32B47A59E248baa07d66d77b0e17
- Molecule
- E3 ubiquitin-protein ligase msl-2
- UniProt
- P50534
- Pockets
- 3 · best druggability 0.60
Structure
1 distinct chain · 17% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase msl-2 | protein | 773 | 17% helix, 6% strand | P50534 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 368 | 0.60 | 0.77 | 34 | empty |
| 2 | 130 | 0.42 | 0.76 | 25 | empty |
| 3 | 64 | 0.33 | 0.77 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4RKH · Structure of the MSL2 CXC domain bound with a specific MRE sequence · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 4RKH · Structure of the MSL2 cxc domain bound with a specific mre sequence · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 2LUA · Solution structure of CXC domain of MSL2 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2LUA · Solution structure of cxc domain of MSL2 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 4RKG · Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 4RKG · Structure of the MSL2 cxc domain bound with a non-specific (GC)6 DNA · an experimental structure of the same protein · chain A against B, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50534
- Elsewhere: UniProt P50534 · AlphaFold DB P50534
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