UniProt P50534
E3 ubiquitin-protein ligase msl-2 (P50534)
E3 ubiquitin-protein ligase msl-2 (UniProt P50534): 6 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P50534
- Protein
- E3 ubiquitin-protein ligase msl-2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
7 records of P50534 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LUA | Solution structure of CXC domain of MSL2 | solution nmr | A | — | — |
| 2LUA | Solution structure of cxc domain of MSL2 | solution nmr | A | — | — |
| 4RKG | Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA | x-ray diffraction | A, B | — | — |
| 4RKG | Structure of the MSL2 cxc domain bound with a non-specific (GC)6 DNA | x-ray diffraction | A, B | — | — |
| 4RKH | Structure of the MSL2 CXC domain bound with a specific MRE sequence | x-ray diffraction | C, D, E, F | — | — |
| 4RKH | Structure of the MSL2 cxc domain bound with a specific mre sequence | x-ray diffraction | C, D, E, F | — | — |
| P50534 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase msl-2 (P50534) | predicted | A | — | 3 (best 0.60) |
Experiment against prediction
- 4RKG chain A against the predicted model P50534: TM-score 0.49, RMSD 2.37 Å
- 4RKG chain A against the predicted model P50534: TM-score 0.49, RMSD 2.37 Å
- 4RKH chain F against the predicted model P50534: TM-score 0.48, RMSD 2.74 Å
- 4RKH chain F against the predicted model P50534: TM-score 0.48, RMSD 2.74 Å
- 4RKH chain C against the predicted model P50534: TM-score 0.47, RMSD 2.63 Å
- 4RKH chain C against the predicted model P50534: TM-score 0.47, RMSD 2.63 Å
- 2LUA chain A against the predicted model P50534: TM-score 0.45, RMSD 2.70 Å
- 2LUA chain A against the predicted model P50534: TM-score 0.45, RMSD 2.70 Å
- 4RKG chain B against the predicted model P50534: TM-score 0.45, RMSD 2.78 Å
- 4RKG chain B against the predicted model P50534: TM-score 0.45, RMSD 2.78 Å
Elsewhere
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