AlphaFold monomer V2.0 prediction for adenylate kinase isoenzyme 1 (P00568)

Structure

1 distinct chain · 61% helix, 12% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 1Z83 · Crystal structure of human AK1A in complex with AP5A · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 1Z83 · Crystal structure of human AK1A in complex with AP5A · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 2C95 · Structure of adenylate kinase 1 in complex with P1,P4-DI(ADENOSINE) tetraphosphate · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 2C95 · Structure of adenylate kinase 1 in complex with P1,P4-di(adenosine) tetraphosphate · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 8X1G · Human adenylate kinase 1 (hAK1) mutant-R97W · an experimental structure of the same protein · chain A against A, TM-score 0.77
• 7DE3 · Human adenylate kinase 1 (HAK1) mutant-R128W · an experimental structure of the same protein · chain A against A, TM-score 0.76
• 7DE3 · Human adenylate kinase 1 (hAK1) mutant-R128W · an experimental structure of the same protein · chain A against A, TM-score 0.76
• 7X7S · Solution structure of human adenylate kinase 1 (HAK1) · an experimental structure of the same protein · chain A against A, TM-score 0.75
• 7X7S · Solution structure of human adenylate kinase 1 (hAK1) · an experimental structure of the same protein · chain A against A, TM-score 0.75

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00568
• Elsewhere: UniProt P00568 · AlphaFold DB P00568