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AlphaFold monomer V2.0 prediction for interleukin-27 receptor subunit alpha (O70394)

Analyse AlphaFold monomer V2.0 prediction for interleukin-27 receptor subunit alpha… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: O70394
Type: protein
Length: 623 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1Eec5F29CD795323506a0E09aeC21c942c4b00a7
Molecule: Interleukin-27 receptor subunit alpha
UniProt: O70394
Pockets: 4 · best druggability 0.58

Structure

1 distinct chain · 12% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interleukin-27 receptor subunit alpha	protein	623	12% helix, 35% strand	O70394

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	139	0.58	0.83	28	empty
2	112	0.44	0.78	22	empty
3	82	0.37	0.76	19	empty
4	81	0.32	0.74	18	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

7Z0L · IL-27 signalling complex · an experimental structure of the same protein · chain A against C, TM-score 0.30
7Z0L · Il-27 signalling complex · an experimental structure of the same protein · chain A against C, TM-score 0.30
7ZG0 · Murine IL-27 in complex with IL-27Ra and a non-competing Nb · an experimental structure of the same protein · chain A against F, TM-score 0.30

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O70394
Elsewhere: UniProt O70394 · AlphaFold DB O70394

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