UniProt O70394
Interleukin-27 receptor subunit alpha (O70394)
Interleukin-27 receptor subunit alpha (UniProt O70394): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O70394
- Protein
- Interleukin-27 receptor subunit alpha
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 21 · 3 records with a druggable one
Structures
4 records of O70394 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Z0L | IL-27 signalling complex | electron microscopy | C | NAG | 6 (best 0.68) |
| 7Z0L | Il-27 signalling complex | electron microscopy | C | NAG | 6 (best 0.68) |
| 7ZG0 | Murine IL-27 in complex with IL-27Ra and a non-competing Nb | x-ray diffraction | E, F | NAG | 9 (best 0.83) |
| O70394 | AlphaFold monomer V2.0 prediction for interleukin-27 receptor subunit alpha (O70394) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
Experiment against prediction
- 7ZG0 chain F against the predicted model O70394: TM-score 0.95, RMSD 1.28 Å
- 7Z0L chain C against the predicted model O70394: TM-score 0.95, RMSD 1.37 Å
- 7Z0L chain C against the predicted model O70394: TM-score 0.95, RMSD 1.37 Å
- 7ZG0 chain E against the predicted model O70394: TM-score 0.95, RMSD 1.25 Å
Elsewhere
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