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AlphaFold monomer V2.0 prediction for serine hydroxymethyltransferase (Q5SI56)

Analyse AlphaFold monomer V2.0 prediction for serine hydroxymethyltransferase (Q5SI56) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q5SI56
Type
protein
Length
407 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9073C46348542FfE4327c3F363F9B51B22058e75
Molecule
Serine hydroxymethyltransferase
UniProt
Q5SI56
Pockets
2 · best druggability 0.48

Structure

1 distinct chain · 47% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASerine hydroxymethyltransferaseprotein40747% helix, 14% strandQ5SI56

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11830.480.7622empty
21920.470.7537empty

Compared structures

  • 8SSY · Room-temperature X-ray structure of Thermus thermophilus serine hydroxymethyltransferase… · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 8SUI · Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase… · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 8SUJ · Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase… · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 9BOW · X-ray structure of Thermus thermophilus serine hydroxymethyltransferase with PLP-L-Ser… · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 9BOH · Room-temperature X-ray structure of Thermus Thermophilus serine hydroxymethyltransferase… · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 9BPE · Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase… · an experimental structure of the same protein · chain A against B, TM-score 0.98

Analyse

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