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AlphaFold monomer V2.0 prediction for glucosidase 2 subunit beta (Q9USH8)

Analyse AlphaFold monomer V2.0 prediction for glucosidase 2 subunit beta (Q9USH8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9USH8
Type
protein
Length
506 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xfb0568570325C9C3F26f51e3A07C58ee55079e46
Molecule
Glucosidase 2 subunit beta
UniProt
Q9USH8
Pockets
4 · best druggability 0.70

Structure

1 distinct chain · 44% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGlucosidase 2 subunit betaprotein50644% helix, 14% strandQ9USH8

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16940.700.7747empty
22500.550.7632empty
3820.400.7817empty
4500.280.7514empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

  • 4XQM · Crystal structure of the mrh domain of glucosidase II beta bound to mannose · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 4XQM · Crystal structure of the MRH domain of Glucosidase II beta bound to mannose · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 2LVX · MRH domain of the Glucosidase II beta subunit from S. pombe · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 2LVX · Mrh domain of the glucosidase II beta subunit from S. pombe · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 2N1H · Solution structure of the GBII-beta MRH domain W409A point mutant · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 2N1H · Solution structure of the gbii-beta mrh domain W409A point mutant · an experimental structure of the same protein · chain A against A, TM-score 0.18

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