Research workbench
AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit beta-3 (P28472)
Analyse AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P28472
- Type
- protein
- Length
- 473 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- Gamma-aminobutyric acid receptor subunit beta-3
- UniProt
- P28472
- Pockets
- 2 · best druggability 0.28
Structure
1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gamma-aminobutyric acid receptor subunit beta-3 | protein | 473 | 36% helix, 23% strand | P28472 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.28 | 0.73 | 16 | empty |
| 2 | 50 | 0.28 | 0.74 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 9EQG · CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA… · an experimental structure of the same protein · chain A against E, TM-score 0.72
- 6I53 · Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6I53 · Cryo-EM structure of the human synaptic ALPHA1-BETA3-GAMMA2 gabaa receptor in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6HUO · Cryoem structure of human full-length heteromeric ALPHA1BETA3GAMMA2L GABA(A)R in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6HUO · CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6HUP · CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6HUP · Cryoem structure of human full-length ALPHA1BETA3GAMMA2L GABA(A)R in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 6HUJ · Cryoem structure of human full-length heteromeric ALPHA1BETA3GAMMA2L GABA(A)R in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.70
- 6HUJ · CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28472
- Elsewhere: UniProt P28472 · AlphaFold DB P28472
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.