Research workbench
AlphaFold monomer V2.0 prediction for protein farnesyltransferase subunit beta (Q02293)
Analyse AlphaFold monomer V2.0 prediction for protein farnesyltransferase subunit beta… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q02293
- Type
- protein
- Length
- 437 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4C5d1f42C76C21E948aC0026486f134eF645C76B
- Molecule
- Protein farnesyltransferase subunit beta
- UniProt
- Q02293
- Pockets
- 6 · best druggability 0.51
Structure
1 distinct chain · 47% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein farnesyltransferase subunit beta | protein | 437 | 47% helix, 7% strand | Q02293 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.51 | 0.79 | 18 | empty |
| 2 | 175 | 0.46 | 0.75 | 23 | empty |
| 3 | 117 | 0.46 | 0.78 | 19 | empty |
| 4 | 134 | 0.38 | 0.73 | 18 | empty |
| 5 | 98 | 0.38 | 0.76 | 23 | empty |
Compared structures
- 1KZP · Protein farnesyltransferase complexed with a farnesylated K-RAS4B peptide product · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1KZP · Protein farnesyltransferase complexed with a farnesylated K-RAS4B peptide product · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1JCS · Crystal structure of rat protein farnesyltransferase complexed with the peptide substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1JCS · Crystal structure of rat protein farnesyltransferase complexed with the peptide substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1TN8 · Protein Farnesyltransferase Complexed with a H-Ras Peptide Substrate and a FPP Analog at… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1TN8 · Protein farnesyltransferase complexed with a H-RAS peptide substrate and a fpp analog at… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1TN7 · Protein farnesyltransferase complexed with a TC21 peptide substrate and a fpp analog at… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1TN7 · Protein Farnesyltransferase Complexed with a TC21 Peptide Substrate and a FPP Analog at… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1JCR · Crystal structure of rat protein farnesyltransferase complexed with the non-substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1JCR · Crystal structure of rat protein farnesyltransferase complexed with the non-substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1KZO · Protein farnesyltransferase complexed with farnesylated K-RAS4B peptide product and… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 1KZO · Protein farnesyltransferase complexed with farnesylated K-RAS4B peptide product and… · an experimental structure of the same protein · chain A against B, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02293
- Elsewhere: UniProt Q02293 · AlphaFold DB Q02293
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