Research workbench
AlphaFold monomer V2.0 prediction for transcription factor ETV6 (P41212)
Analyse AlphaFold monomer V2.0 prediction for transcription factor ETV6 (P41212) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P41212
- Type
- protein
- Length
- 452 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e7B5D87BCfF3f2778427eC04CAcD586303e4B9c
- Molecule
- Transcription factor ETV6
- UniProt
- P41212
- Pockets
- 4 · best druggability 0.51
Structure
1 distinct chain · 24% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription factor ETV6 | protein | 452 | 24% helix, 4% strand | P41212 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.51 | 0.80 | 21 | empty |
| 2 | 71 | 0.51 | 0.85 | 17 | empty |
| 3 | 143 | 0.43 | 0.75 | 23 | empty |
| 4 | 84 | 0.32 | 0.74 | 14 | empty |
Compared structures
- 7N2B · A DARPin semi-rigidly fused to the 3TEL crystallization chaperone · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 7N2B · A darpin semi-rigidly fused to the 3TEL crystallization chaperone · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 5L0P · Symmetry-based assembly of a two-dimensional protein lattice · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 5L0P · Symmetry-based assembly of a two-dimensional protein lattice · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 9E4Q · A DARPin fused to the 3TEL crystallization chaperone via a gly-gly-gly fusion · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2DAO · Solution structure of ETS domain Transcriptional factor ETV6 protein · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2DAO · Solution structure of ets domain transcriptional factor ETV6 protein · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 9CPL · The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the… · an experimental structure of the same protein · chain A against A, TM-score 0.22
- 9DOC · The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 8FZV · The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly… · an experimental structure of the same protein · chain A against B, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41212
- Elsewhere: UniProt P41212 · AlphaFold DB P41212
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