AlphaFold monomer V2.0 prediction for elongation factor tu 2 (P0CE48)

Structure

1 distinct chain · 24% helix, 36% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Compared structures

• 5WE4 · 70S ribosome-EF-Tu wt complex with GppNHp · an experimental structure of the same protein · chain A against z, TM-score 0.94
• 5WE6 · 70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA · an experimental structure of the same protein · chain A against z, TM-score 0.94
• 5WDT · 70S ribosome-EF-Tu H84A complex with GppNHp · an experimental structure of the same protein · chain A against z, TM-score 0.94
• 5WFK · 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3) · an experimental structure of the same protein · chain A against z, TM-score 0.93
• 1OB2 · E. COLI elongation factor ef-tu complexed with the antibiotic kirromycin, a GTP analog… · an experimental structure of the same protein · chain A against A, TM-score 0.93
• 1OB2 · E. coli elongation factor EF-Tu complexed with the antibiotic kirromycin, a GTP analog… · an experimental structure of the same protein · chain A against A, TM-score 0.93
• 4V6K · Structural insights into cognate vs. near-cognate discrimination during decoding. · an experimental structure of the same protein · chain A against BC, TM-score 0.89
• 5AFI · 2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM · an experimental structure of the same protein · chain A against z, TM-score 0.87
• 4V6L · Structural insights into cognate vs. near-cognate discrimination during decoding. · an experimental structure of the same protein · chain A against AC, TM-score 0.86
• 7ABZ · Structure of pre-accomodated trans-translation complex on E. coli stalled ribosome. · an experimental structure of the same protein · chain A against 6, TM-score 0.86
• 6EZE · The open conformation of E.COLI elongation factor tu in complex with gdpnp. · an experimental structure of the same protein · chain A against A, TM-score 0.58
• 6EZE · The open conformation of E.coli Elongation Factor Tu in complex with GDPNP. · an experimental structure of the same protein · chain A against A, TM-score 0.58

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0CE48
• Elsewhere: UniProt P0CE48 · AlphaFold DB P0CE48