Research workbench
AlphaFold monomer V2.0 prediction for DNA polymerase I, thermostable (P19821)
Analyse AlphaFold monomer V2.0 prediction for DNA polymerase I, thermostable (P19821) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P19821
- Type
- protein
- Length
- 832 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc59A47c8d9b1543054659D2a0C21B0fdf18F05A4
- Molecule
- DNA polymerase I, thermostable
- UniProt
- P19821
- Pockets
- 8 · best druggability 0.66
Structure
1 distinct chain · 52% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase I, thermostable | protein | 832 | 52% helix, 12% strand | P19821 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.66 | 0.86 | 28 | empty |
| 2 | 426 | 0.60 | 0.75 | 42 | empty |
| 3 | 187 | 0.58 | 0.81 | 26 | empty |
| 4 | 272 | 0.54 | 0.76 | 31 | empty |
| 5 | 160 | 0.47 | 0.77 | 35 | empty |
Compared structures
- 4XIU · Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant with DNA… · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 4XIU · Binary complex structure of klenow fragment of taq DNA polymerase I707L mutant with DNA… · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 4KTQ · Binary complex of the large fragment of DNA polymerase I from T. aquaticus bound to a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4KTQ · Binary complex of the large fragment of DNA polymerase I from T. aquaticus bound to a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3RRH · Ternary structure of the large fragment of taq DNA polymerase bound to an abasic site and… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3RRH · Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4C8K · Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4C8K · Crystal structure of the large fragment of DNA polymerase I from thermus aquaticus in a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4C8O · Binary complex of the large fragment of DNA polymerase I from Thermus Aquaticus with the… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4C8O · Binary complex of the large fragment of DNA polymerase I from thermus aquaticus with the… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3LWM · Structure of the large fragment of thermus aquaticus DNA polymerase I in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3LWM · Structure of the large fragment of thermus aquaticus DNA polymerase I in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19821
- Elsewhere: UniProt P19821 · AlphaFold DB P19821
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