UniProt X5E0F1
Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase (X5E0F1)
Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase (UniProt X5E0F1), EC 2.5.1.48, 4.4.1.1: 30 experimental structures on GenesisL1, 6 ligands bound, 47 pockets. Binding sites, pockets, druggability and 3D…
- UniProt
- X5E0F1
- Protein
- Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase
- EC
- 2.5.1.48, 4.4.1.1, 4.4.1.8
- Experimental structures
- 30
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 47 · 10 records with a druggable one
Structures
30 records of X5E0F1 in the MolNFT archive: 30 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7MCB | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase Holoenzyme | x-ray diffraction | H | PLP, NA | 2 (best 0.54) |
| 7MCB | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme | x-ray diffraction | H | PLP, NA | — |
| 7MCL | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, PLP bound | x-ray diffraction | H | PLP, NA | 2 (best 0.65) |
| 7MCL | Crystal structure of staphylococcus aureus cystathionine gamma-lyase, plp bound | x-ray diffraction | H | PLP, NA | — |
| 7MCN | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme with High HEPES | x-ray diffraction | H | PLP, NA | 3 (best 0.52) |
| 7MCN | Crystal structure of staphylococcus aureus cystathionine gamma-lyase, holoenzyme with high hepes | x-ray diffraction | H | PLP, NA | — |
| 7MCP | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme dimer | x-ray diffraction | A, H | PLP, NA | 7 (best 0.73) |
| 7MCP | Crystal structure of staphylococcus aureus cystathionine gamma-lyase, holoenzyme dimer | x-ray diffraction | A, H | PLP, NA | — |
| 7MCQ | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, AOAA-bound enzyme in dimeric… | x-ray diffraction | A, H | IK2, NA | 8 (best 0.76) |
| 7MCQ | Crystal structure of staphylococcus aureus cystathionine gamma lyase, aoaa-bound enzyme in dimeric… | x-ray diffraction | A, H | IK2, NA | — |
| 7MCT | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL1 | x-ray diffraction | H | LB6, PLP, NA | 3 (best 0.55) |
| 7MCT | Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound NL1 | x-ray diffraction | H | LB6, PLP, NA | — |
| 7MCU | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL2 | x-ray diffraction | H | PLP, YXA, NA | 3 (best 0.53) |
| 7MCU | Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound NL2 | x-ray diffraction | H | PLP, YXA, NA | — |
| 7MCY | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL3 | x-ray diffraction | H | PLP, NL3, NA | 2 (best 0.53) |
| 7MCY | Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound NL3 | x-ray diffraction | H | PLP, NL3, NA | — |
| 7MD0 | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme in the presence of… | x-ray diffraction | H | PLP, NA | 2 (best 0.51) |
| 7MD0 | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme in the presence of… | x-ray diffraction | H | PLP, NA | — |
| 7MD1 | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant | x-ray diffraction | H | PLP, NA | 3 (best 0.51) |
| 7MD1 | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant | x-ray diffraction | H | PLP, NA | — |
| 7MD6 | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant… | x-ray diffraction | H | LB6, NA | 3 (best 0.47) |
| 7MD6 | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant… | x-ray diffraction | H | LB6, NA | — |
| 7MD8 | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant… | x-ray diffraction | H | PLP, NA | 2 (best 0.49) |
| 7MD8 | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant… | x-ray diffraction | H | PLP, NA | — |
| 7MD9 | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant | x-ray diffraction | H | NA | 2 (best 0.48) |
| 7MD9 | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant | x-ray diffraction | H | NA | — |
| 7MDA | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant… | x-ray diffraction | H | LB6, NA | 3 (best 0.50) |
| 7MDA | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant… | x-ray diffraction | H | LB6, NA | — |
| 7MDB | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant… | x-ray diffraction | H | YXA, PLP, NA | 2 (best 0.50) |
| 7MDB | Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant… | x-ray diffraction | H | YXA, PLP, NA | — |
Ligands
- NA · Sodium ion · in 30 records
- PLP · Pyridoxal-5'-phosphate · in 22 records
- LB6 · N-[(6-bromo-1H-indol-1-yl)acetyl]glycine · in 6 records
- YXA · 5-[(6-bromo-1H-indol-1-yl)methyl]-2-methylfuran-3-carboxylic acid · in 4 records
- IK2 · 4'-deoxy-4'-acetylyamino-pyridoxal-5'-phosphate · in 2 records
- NL3 · 3-{[6-(7-chloro-1-benzothiophen-2-yl)-1H-indol-1-yl]methyl}-1H-pyrazole-5-carboxylic acid · in 2 records
Elsewhere
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