UniProt W8RJF9
Fusion glycoprotein F0 (W8RJF9)
Fusion glycoprotein F0 (UniProt W8RJF9): 25 experimental structures on GenesisL1, 10 ligands bound, 38 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- W8RJF9
- Protein
- Fusion glycoprotein F0
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 38 · 2 records with a druggable one
Structures
25 records of W8RJF9 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KWW | Crystal Structure of Inhibitor JNJ-53718678 In Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | NAG, SO4, 6YA | 2 (best 0.45) |
| 5KWW | Crystal structure of inhibitor jnj-53718678 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | NAG, SO4, 6YA | — |
| 6EAD | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | 3 (best 0.38) |
| 6EAD | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | — |
| 6EAE | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | SO4 | 2 (best 0.42) |
| 6EAE | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | SO4 | — |
| 6EAF | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | A, B, C | NAG, SO4 | — |
| 6EAG | Crystal structure of fusion inhibitor jnj-2408068 in complex with human respiratory syncytial virus… | x-ray diffraction | F | SO4, 5NK | — |
| 6EAH | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | A, B, C | NAG, FUC, SO4 | — |
| 6EAI | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | A, B, C | NAG, SO4 | — |
| 6EAJ | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | SO4 | — |
| 6EAK | Crystal structure of fusion inhibitor jnj-2408068 in complex with human respiratory syncytial virus… | x-ray diffraction | F | SO4, NI, 5NK | 2 (best 0.46) |
| 6EAK | Crystal structure of fusion inhibitor jnj-2408068 in complex with human respiratory syncytial virus… | x-ray diffraction | F | SO4, NI, 5NK | — |
| 6EAL | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | SO4 | — |
| 6EAM | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | 3 (best 0.46) |
| 6EAM | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | — |
| 6EAN | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | 3 (best 0.53) |
| 6EAN | Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant… | x-ray diffraction | F | NAG, SO4 | — |
| 6VKD | Crystal Structure of Inhibitor JNJ-36689282 in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | F | R0P, CL, SO4 | 2 (best 0.30) |
| 6VKD | Crystal structure of inhibitor jnj-36689282 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | R0P, CL, SO4 | — |
| 6VKE | Crystal structure of inhibitor jnj-40012665 in complex with prefusion rsv F glycoprotein | x-ray diffraction | F | R0S, CL, SO4 | — |
| 7LUE | Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442 | electron microscopy | A, B, C | — | 20 (best 0.85) |
| 7LUE | Prefusion rsv F glycoprotein bound by neutralizing site V-directed antibody adi-14442 | electron microscopy | A, B, C | — | — |
| 7LVW | Structure of rsv F in complex with vhh CL184 | x-ray diffraction | A, B, C, D, E, F | NAG, CL | — |
| 9BJM | Crystal Structure of Inhibitor 5c in Complex with Prefusion RSV F Glycoprotein | x-ray diffraction | A | A1APZ | 1 (best 0.31) |
Ligands
- SO4 · Sulfate ion · in 21 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 12 records
- CL · Chloride ion · in 4 records
- 5NK · 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol · in 3 records
- 6YA · 3-[[5-chloranyl-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-[2,2,2-tris(fluoranyl)ethyl]imidazo[4,5-c]pyridin-2-one · in 2 records
- NI · Nickel (II) ion · in 2 records
- R0P · 1-cyclopropyl-3-({1-[3-(methylsulfonyl)propyl]-1H-pyrrolo[3,2-c]pyridin-2-yl}methyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one · in 2 records
- A1APZ · 1'-{[5-chloro-1-(4,4,4-trifluorobutyl)-1H-1,3-benzimidazol-2-yl]methyl}-1-(methanesulfonyl)spiro[azetidine-3,3'-indol]-2'(1'H)-one · in 1 record
- FUC · alpha-L-fucopyranose · in 1 record
- R0S · 4-(5-chloro-2-{[1-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3H-imidazo[4,5-c]pyridin-3-yl]methyl}-1H-indol-1-yl)butanenitrile · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.