UniProt U3N7D8
Transient receptor potential cation channel subfamily c member 4a (U3N7D8)
Transient receptor potential cation channel subfamily c member 4a (UniProt U3N7D8): 12 experimental structures on GenesisL1, 7 ligands bound, 120 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- U3N7D8
- Protein
- Transient receptor potential cation channel subfamily c member 4a
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 120 · 6 records with a druggable one
Structures
12 records of U3N7D8 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G1K | Electron cryo-microscopy structure of the canonical TRPC4 ion channel | electron microscopy | A, B, C, D | Y01, 44E | 20 (best 0.87) |
| 6G1K | Electron cryo-microscopy structure of the canonical TRPC4 ion channel | electron microscopy | A, B, C, D | Y01, 44E | — |
| 7B05 | TRPC4 in complex with inhibitor GFB-8749 | electron microscopy | A, B, C, D | SJQ, CA, 44E | 20 (best 0.85) |
| 7B05 | TRPC4 in complex with inhibitor gfb-8749 | electron microscopy | A, B, C, D | CA, 44E | — |
| 7B0J | TRPC4 in LMNG detergent | electron microscopy | A, B, C, D | LPP, CA | 20 (best 0.85) |
| 7B0J | TRPC4 in lmng detergent | electron microscopy | A, B, C, D | LPP, CA | — |
| 7B0S | TRPC4 in complex with inhibitor GFB-8438 | electron microscopy | A, B, C, D | S9Q, CA, 44E | 20 (best 0.84) |
| 7B0S | TRPC4 in complex with inhibitor gfb-8438 | electron microscopy | A, B, C, D | S9Q, CA, 44E | — |
| 7B16 | TRPC4 in complex with inhibitor GFB-9289 | electron microscopy | A, B, C, D | SKQ, CA, LPP | 20 (best 0.84) |
| 7B16 | TRPC4 in complex with inhibitor gfb-9289 | electron microscopy | A, B, C, D | SKQ, CA, LPP | — |
| 7B1G | TRPC4 in complex with Calmodulin | electron microscopy | A, B, C, D | CA, 44E | 20 (best 0.85) |
| 7B1G | TRPC4 in complex with calmodulin | electron microscopy | A, B, C, D | CA, 44E | — |
Ligands
- CA · Calcium ion · in 10 records
- 44E · (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate · in 8 records
- LPP · 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate · in 4 records
- S9Q · 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl) phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one · in 2 records
- SKQ · 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one · in 2 records
- Y01 · Cholesterol hemisuccinate · in 2 records
- SJQ · 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one · in 1 record
Elsewhere
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