UniProt T0D7A2
CRISPR-associated endonuclease C2c1 (T0D7A2)
CRISPR-associated endonuclease C2c1 (UniProt T0D7A2), EC 3.1.-.-: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- T0D7A2
- Protein
- CRISPR-associated endonuclease C2c1
- EC
- 3.1.-.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
9 records of T0D7A2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5U30 | Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex | x-ray diffraction | A | SO4 | 20 (best 0.83) |
| 5U30 | Crystal structure of AACC2C1-sgrna-extended target DNA ternary complex | x-ray diffraction | A | SO4 | — |
| 5U31 | Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex | x-ray diffraction | A | SO4 | — |
| 5U31 | Crystal structure of AACC2C1-sgrna-8MER substrate DNA ternary complex | x-ray diffraction | A | SO4 | — |
| 5U33 | Crystal structure of AACC2C1-sgrna-extended non-target DNA ternary complex | x-ray diffraction | A | SO4 | — |
| 5U34 | Crystal structure of AacC2c1-sgRNA binary complex | x-ray diffraction | A | — | — |
| 5U34 | Crystal structure of AACC2C1-sgrna binary complex | x-ray diffraction | A | — | — |
| 5WQE | Crystal structure of alicyclobacillus acidoterrestris C2C1 in complex with single-guide RNA at 3.1… | x-ray diffraction | A | — | — |
| T0D7A2 | AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS12B (T0D7A2) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 5 records
Experiment against prediction
- 5U33 chain A against the predicted model T0D7A2: TM-score 0.99, RMSD 0.77 Å
- 5U31 chain A against the predicted model T0D7A2: TM-score 0.99, RMSD 0.77 Å
- 5U31 chain A against the predicted model T0D7A2: TM-score 0.99, RMSD 0.77 Å
- 5U30 chain A against the predicted model T0D7A2: TM-score 0.99, RMSD 0.78 Å
- 5U30 chain A against the predicted model T0D7A2: TM-score 0.99, RMSD 0.78 Å
- 5U34 chain A against the predicted model T0D7A2: TM-score 0.94, RMSD 2.92 Å
- 5U34 chain A against the predicted model T0D7A2: TM-score 0.94, RMSD 2.92 Å
- 5WQE chain A against the predicted model T0D7A2: TM-score 0.92, RMSD 3.38 Å
Elsewhere
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