UniProt S5UH55
Transient receptor potential melastatin 5 (S5UH55)
Transient receptor potential melastatin 5 (UniProt S5UH55): 11 experimental structures on GenesisL1, 5 ligands bound, 80 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- S5UH55
- Protein
- Transient receptor potential melastatin 5
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 80 · 4 records with a druggable one
Structures
11 records of S5UH55 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7MBP | Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mM EDTA | electron microscopy | A, B, C, D | NAG, YUV, YUY | 20 (best 0.83) |
| 7MBP | Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mm edta | electron microscopy | A, B, C, D | NAG, YUV, YUY | — |
| 7MBQ | Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium | electron microscopy | A, B, C, D | NAG, CA, YUV, YUY | 20 (best 0.85) |
| 7MBQ | Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mm calcium | electron microscopy | A, B, C, D | NAG, CA, YUV, YUY | — |
| 7MBR | Cryo-EM structure of zebrafish TRPM5 in the presence of 6 um calcium (apo state) | electron microscopy | A, B, C, D | NAG, YUV, YUY | — |
| 7MBS | Cryo-EM structure of zebrafish TRPM5 in the presence of 6 um calcium (open state) | electron microscopy | A, B, C, D | NAG, CA, YUV, YUY | — |
| 7MBT | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (low calcium… | electron microscopy | A, B, C, D | NAG, YUY, YUV | 20 (best 0.82) |
| 7MBT | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mm calcium (low calcium… | electron microscopy | A, B, C, D | NAG, YUY, YUV | — |
| 7MBU | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium… | electron microscopy | A, B, C, D | NAG, CA, YUY, YUV | 20 (best 0.87) |
| 7MBU | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mm calcium (high calcium… | electron microscopy | A, B, C, D | NAG, CA, YUY, YUV | — |
| 7MBV | Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mm calcium and 0.5 mm ndna | electron microscopy | A, B, C, D | NAG, CA, YUS, YUV, YUY | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 11 records
- YUV · (25R)-14beta,17beta-spirost-5-en-3beta-ol · in 11 records
- YUY · (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside · in 11 records
- CA · Calcium ion · in 6 records
- YUS · N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-(naphthalen-1-yl)acetohydrazide · in 1 record
Elsewhere
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