Ligand · YUV

YUV · (25R)-14beta,17beta-spirost-5-en-3beta-ol

YUV, (25R)-14beta,17beta-spirost-5-en-3beta-ol (C27 H42 O3, 414.6 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component: YUV
Formula: C27 H42 O3
Class: ligand
Structures: 14
PDB entries: 7

Binding sites

YUV in 14 structures; the first of them:

7MBP · Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mM EDTA · YUV A1502 · binds ILE888, ASP889, PHE892
7MBQ · Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium · YUV A1504 · binds ILE888, ASP889, PHE892
7MBR · Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (apo state) · YUV A1502 · binds ILE888, ASP889, PHE892
7MBS · Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (open state) · YUV A1504 · binds ILE888, ASP889, PHE892
7MBT · Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (low… · YUV A1503 · binds ILE888, ASP889, PHE892, LEU896
7MBU · Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high… · YUV A1504 · binds ILE888, ASP889, PHE892, LEU896
7MBV · Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium and 0.5 mM NDNA · YUV A1505 · binds ILE888, ASP889, PHE892
7MBP · Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mm edta · YUV A1502 · binds ILE888, ASP889, PHE892
7MBQ · Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mm calcium · YUV A1504 · binds PHE892
7MBR · Cryo-EM structure of zebrafish TRPM5 in the presence of 6 um calcium (apo state) · YUV A1502 · binds ILE888, ASP889, PHE892

Residues it binds most

PHE 56, ASP 44, ILE 41, LEU 8 (residue and the binding sites it lines).

Found with

YUY · (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
CA · Calcium ion
YUS · N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-(naphthalen-1-yl)acetohydrazide

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