UniProt Q9Y606
TRNA pseudouridine synthase a (Q9Y606)
TRNA pseudouridine synthase a (UniProt Q9Y606): 10 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y606
- Protein
- TRNA pseudouridine synthase a
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of Q9Y606 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IQM | Crystal structure of the catalytic domain of human Pus1 | x-ray diffraction | A | — | — |
| 4IQM | Crystal structure of the catalytic domain of human PUS1 | x-ray diffraction | A | — | — |
| 4ITS | Crystal structure of the catalytic domain of human Pus1 with MES in the active site | x-ray diffraction | A | — | — |
| 4ITS | Crystal structure of the catalytic domain of human PUS1 with mes in the active site | x-ray diffraction | A | — | — |
| 4J37 | Crystal structure of the catalytic domain of human Pus1 | x-ray diffraction | A | — | — |
| 4J37 | Crystal structure of the catalytic domain of human PUS1 | x-ray diffraction | A | — | — |
| 4NZ6 | Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p)… | x-ray diffraction | A, B | — | — |
| 4NZ6 | Steroid receptor RNA activator (sra) modification by the human pseudouridine synthase 1 (HPUS1P)… | x-ray diffraction | A, B | — | — |
| 4NZ7 | Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p)… | x-ray diffraction | A | — | — |
| 4NZ7 | Steroid receptor RNA activator (sra) modification by the human pseudouridine synthase 1 (HPUS1P)… | x-ray diffraction | A | — | — |
| Q9Y606 | AlphaFold monomer V2.0 prediction for tRNA pseudouridine synthase a (Q9Y606) | predicted | A | — | 3 (best 0.51) |
Experiment against prediction
- 4NZ6 chain A against the predicted model Q9Y606: TM-score 0.98, RMSD 0.83 Å
- 4NZ6 chain A against the predicted model Q9Y606: TM-score 0.98, RMSD 0.83 Å
- 4NZ6 chain B against the predicted model Q9Y606: TM-score 0.98, RMSD 0.89 Å
- 4NZ6 chain B against the predicted model Q9Y606: TM-score 0.98, RMSD 0.89 Å
- 4NZ7 chain A against the predicted model Q9Y606: TM-score 0.98, RMSD 1.09 Å
- 4NZ7 chain A against the predicted model Q9Y606: TM-score 0.98, RMSD 1.09 Å
- 4IQM chain A against the predicted model Q9Y606: TM-score 0.97, RMSD 1.32 Å
- 4IQM chain A against the predicted model Q9Y606: TM-score 0.97, RMSD 1.32 Å
- 4J37 chain A against the predicted model Q9Y606: TM-score 0.97, RMSD 1.07 Å
- 4J37 chain A against the predicted model Q9Y606: TM-score 0.97, RMSD 1.07 Å
Elsewhere
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