UniProt Q9Y5K2
Kallikrein-4 (Q9Y5K2)
Kallikrein-4 (UniProt Q9Y5K2), EC 3.4.21.-: 21 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5K2
- Protein
- Kallikrein-4
- EC
- 3.4.21.-
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
22 records of Q9Y5K2 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BDG | Human Kallikrein 4 complex with nickel and p-aminobenzamidine | x-ray diffraction | A, B | — | — |
| 2BDG | Human kallikrein 4 complex with nickel and P-aminobenzamidine | x-ray diffraction | A, B | — | — |
| 2BDH | Human Kallikrein 4 complex with zinc and p-aminobenzamidine | x-ray diffraction | A, B, C, D | — | — |
| 2BDH | Human kallikrein 4 complex with zinc and P-aminobenzamidine | x-ray diffraction | A, B, C, D | — | — |
| 2BDI | Human Kallikrein 4 complex with cobalt and p-aminobenzamidine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 2BDI | Human kallikrein 4 complex with cobalt and P- aminobenzamidine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 4K1E | Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with a modified… | x-ray diffraction | A | — | — |
| 4K1E | Atomic resolution crystal structures of kallikrein-related peptidase 4 complexed with a modified… | x-ray diffraction | A | — | — |
| 4K8Y | Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower… | x-ray diffraction | A | — | — |
| 4K8Y | Atomic resolution crystal structures of kallikrein-related peptidase 4 complexed with sunflower… | x-ray diffraction | A | — | — |
| 4KEL | Atomic resolution crystal structure of Kallikrein-Related Peptidase 4 complexed with a modified… | x-ray diffraction | A | — | — |
| 4KEL | Atomic resolution crystal structure of kallikrein-related peptidase 4 complexed with a modified… | x-ray diffraction | A | — | — |
| 4KGA | Crystal structure of kallikrein-related peptidase 4 | x-ray diffraction | A, B | — | — |
| 4KGA | Crystal structure of kallikrein-related peptidase 4 | x-ray diffraction | A, B | — | — |
| 6KBR | Crystal structure of human KLK4 and SPINK2 derived KLK4 inhibitor complex | x-ray diffraction | A | — | — |
| 6NVB | Crystal structure of the inhibitor-free form of the serine protease kallikrein-4 | x-ray diffraction | A, B, C, D | SO4 | — |
| 7JQK | Crystal structure of the R64A mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with… | x-ray diffraction | E | CD | 3 (best 0.60) |
| 7JQK | Crystal structure of the R64A mutant of bauhinia bauhinioides kallikrein inhibitor complexed with… | x-ray diffraction | E | CD | — |
| 7JQN | Crystal structure of the R64M mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with… | x-ray diffraction | E | CD | — |
| 7JQN | Crystal structure of the R64M mutant of bauhinia bauhinioides kallikrein inhibitor complexed with… | x-ray diffraction | E | CD | — |
| 7JQO | Crystal structure of the R64D mutant of bauhinia bauhinioides kallikrein inhibitor complexed with… | x-ray diffraction | E | CD | — |
| Q9Y5K2 | AlphaFold monomer V2.0 prediction for kallikrein-4 (Q9Y5K2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7JQO chain E against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.30 Å
- 7JQK chain E against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.30 Å
- 7JQK chain E against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.30 Å
- 7JQN chain E against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.31 Å
- 7JQN chain E against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.31 Å
- 6NVB chain A against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.32 Å
- 4K8Y chain A against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.32 Å
- 4K8Y chain A against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.32 Å
- 2BDI chain A against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.37 Å
- 2BDI chain A against the predicted model Q9Y5K2: TM-score 1.00, RMSD 0.37 Å
Elsewhere
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