UniProt Q9Y580
RNA-binding protein 7 (Q9Y580)
RNA-binding protein 7 (UniProt Q9Y580): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y580
- Protein
- RNA-binding protein 7
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 0 records with a druggable one
Structures
13 records of Q9Y580 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M8H | RRM domain of human RBM7 | solution nmr | A | — | — |
| 2M8H | Rrm domain of human RBM7 | solution nmr | A | — | — |
| 5IQQ | Crystal structure of the human RBM7 RRM domain | x-ray diffraction | A, B, C, D, E | — | 5 (best 0.40) |
| 5IQQ | Crystal structure of the human RBM7 rrm domain | x-ray diffraction | A, B, C, D, E | — | — |
| 5LXR | Structure of the minimal RBM7 - ZCCHC8 Complex | x-ray diffraction | A | SM, BR, CL | — |
| 5LXR | Structure of the minimal RBM7 - ZCCHC8 complex | x-ray diffraction | A | SM, BR, CL | — |
| 5LXY | Structure of the minimal RBM7 - ZCCHC8 Complex | x-ray diffraction | A, B, E, G, I, K, M | BR | — |
| 5LXY | Structure of the minimal RBM7 - ZCCHC8 complex | x-ray diffraction | A, B, E, G, I, K, M | BR | — |
| 7S7B | Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) | electron microscopy | C, G | — | — |
| 7S7B | Human nuclear exosome targeting (next) complex homodimer bound to RNA (substrate 1) | electron microscopy | C, G | — | — |
| 7S7C | Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) | electron microscopy | C | — | 2 (best 0.49) |
| 7S7C | Human nuclear exosome targeting (next) complex bound to RNA (substrate 2) | electron microscopy | C | — | — |
| Q9Y580 | AlphaFold monomer V2.0 prediction for RNA-binding protein 7 (Q9Y580) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5LXY chain B against the predicted model Q9Y580: TM-score 0.98, RMSD 0.45 Å
- 5LXY chain B against the predicted model Q9Y580: TM-score 0.98, RMSD 0.45 Å
- 5LXY chain G against the predicted model Q9Y580: TM-score 0.98, RMSD 0.44 Å
- 5LXY chain G against the predicted model Q9Y580: TM-score 0.98, RMSD 0.44 Å
- 5IQQ chain E against the predicted model Q9Y580: TM-score 0.97, RMSD 0.56 Å
- 5IQQ chain E against the predicted model Q9Y580: TM-score 0.97, RMSD 0.56 Å
- 5LXY chain K against the predicted model Q9Y580: TM-score 0.97, RMSD 0.54 Å
- 5LXY chain K against the predicted model Q9Y580: TM-score 0.97, RMSD 0.54 Å
- 5LXY chain E against the predicted model Q9Y580: TM-score 0.97, RMSD 0.61 Å
- 5LXY chain E against the predicted model Q9Y580: TM-score 0.97, RMSD 0.61 Å
Elsewhere
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