UniProt Q9Y3B8
Oligoribonuclease, mitochondrial (Q9Y3B8)
Oligoribonuclease, mitochondrial (UniProt Q9Y3B8), EC 3.1.-.-: 20 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9Y3B8
- Protein
- Oligoribonuclease, mitochondrial
- EC
- 3.1.-.-
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 29 · 8 records with a druggable one
Structures
21 records of Q9Y3B8 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J7Y | Human mitochondrial Oligoribonuclease in complex with DNA | x-ray diffraction | B, A | MG | 2 (best 0.34) |
| 6J7Y | Human mitochondrial oligoribonuclease in complex with DNA | x-ray diffraction | B, A | MG | — |
| 6J7Z | Human mitochondrial Oligoribonuclease in complex with RNA | x-ray diffraction | A, B | MG | 3 (best 0.48) |
| 6J7Z | Human mitochondrial oligoribonuclease in complex with RNA | x-ray diffraction | A, B | MG | — |
| 6J80 | Human mitochondrial Oligoribonuclease in complex with poly-dT DNA | x-ray diffraction | A, B | MG | 2 (best 0.65) |
| 6J80 | Human mitochondrial oligoribonuclease in complex with poly-dt DNA | x-ray diffraction | A, B | MG | — |
| 6N6I | Human REXO2 bound to pGG | x-ray diffraction | A, B | NA | 3 (best 0.54) |
| 6N6I | Human REXO2 bound to pgg | x-ray diffraction | A, B | NA | — |
| 6N6J | Human REXO2 bound to pAA | x-ray diffraction | A, B | NA | 3 (best 0.53) |
| 6N6J | Human REXO2 bound to paa | x-ray diffraction | A, B | NA | — |
| 6N6K | Human REXO2 bound to pAG | x-ray diffraction | A, B | NA | 3 (best 0.52) |
| 6N6K | Human REXO2 bound to pag | x-ray diffraction | A, B | NA | — |
| 6RCI | Crystal structure of REXO2 | x-ray diffraction | A, B | — | 1 (best 0.69) |
| 6RCI | Crystal structure of REXO2 | x-ray diffraction | A, B | — | — |
| 6RCL | Crystal structure of REXO2-D199A-AA | x-ray diffraction | A, B | ZN, MG | 3 (best 0.56) |
| 6RCL | Crystal structure of REXO2-D199A-aa | x-ray diffraction | A, B | ZN, MG | — |
| 6RCN | Crystal structure of REXO2-D199A-dAdA | x-ray diffraction | A, B | ZN, MG | 3 (best 0.56) |
| 6RCN | Crystal structure of REXO2-D199A-dada | x-ray diffraction | A, B | ZN, MG | — |
| 6STY | Human REXO2 exonuclease in complex with RNA. | x-ray diffraction | A, B, D, E | CA | 5 (best 0.66) |
| 6STY | Human REXO2 exonuclease in complex with RNA. | x-ray diffraction | A, B, D, E | CA | — |
| Q9Y3B8 | AlphaFold monomer V2.0 prediction for oligoribonuclease, mitochondrial (Q9Y3B8) | predicted | A | — | 1 (best 0.46) |
Ligands
Experiment against prediction
- 6N6I chain A against the predicted model Q9Y3B8: TM-score 1.00, RMSD 0.36 Å
- 6N6I chain A against the predicted model Q9Y3B8: TM-score 1.00, RMSD 0.36 Å
- 6N6J chain A against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.37 Å
- 6N6J chain A against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.37 Å
- 6N6K chain A against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.40 Å
- 6N6K chain A against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.40 Å
- 6N6J chain B against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.41 Å
- 6N6J chain B against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.41 Å
- 6J7Z chain B against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.39 Å
- 6J7Z chain B against the predicted model Q9Y3B8: TM-score 0.99, RMSD 0.39 Å
Elsewhere
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