UniProt Q9XJ43
Hyoscyamine 6-beta-hydroxylase (Q9XJ43)
Hyoscyamine 6-beta-hydroxylase (UniProt Q9XJ43), EC 1.14.11.11: 9 experimental structures on GenesisL1, 8 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9XJ43
- Protein
- Hyoscyamine 6-beta-hydroxylase
- EC
- 1.14.11.11
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 22 · 8 records with a druggable one
Structures
9 records of Q9XJ43 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8CV8 | Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and hyoscyamine | x-ray diffraction | A | SR, FE2, AKG, HYO | 2 (best 0.82) |
| 8CV9 | Structure of Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and hyoscyamine | x-ray diffraction | A | HYO, V, O, SR | 3 (best 0.81) |
| 8CVA | Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, succinate, and 6-OH-hyoscyamine | x-ray diffraction | A | FE2, OVR, SR | — |
| 8CVB | Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and… | x-ray diffraction | A | FE2, AKG, OVR, SR | 2 (best 0.81) |
| 8CVC | Structure of Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and 6-OH-hyoscyamine | x-ray diffraction | A | OVR, V, O, SR | 3 (best 0.81) |
| 8CVD | Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, succinate, and scopolamine | x-ray diffraction | A | FE2, OW0, SR | 3 (best 0.81) |
| 8CVF | Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and… | x-ray diffraction | A | HYO, V, O, SR | 3 (best 0.83) |
| 8CVG | Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and… | x-ray diffraction | A | FE2, AKG, OVR, SR | 3 (best 0.83) |
| 8CVH | Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and… | x-ray diffraction | A | OVR, V, SR | 3 (best 0.83) |
Ligands
- SR · Strontium ion · in 9 records
- FE2 · Fe (II) ion · in 5 records
- OVR · (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate · in 5 records
- V · Vanadium ion · in 4 records
- AKG · 2-oxoglutaric acid · in 3 records
- HYO · [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate · in 3 records
- O · Oxygen atom · in 3 records
- OW0 · (1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate · in 1 record
Elsewhere
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