UniProt Q9XAY4
Beta-lactamase VIM-1 (Q9XAY4)
Beta-lactamase VIM-1 (UniProt Q9XAY4): 71 experimental structures on GenesisL1, 66 ligands bound, 66 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9XAY4
- Protein
- Beta-lactamase VIM-1
- Experimental structures
- 71
- Predicted models
- 0
- Ligands
- 66
- Pockets
- 66 · 58 records with a druggable one
Structures
71 records of Q9XAY4 in the MolNFT archive: 71 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5N5G | Crystal structure of di-zinc metallo-beta-lactamase VIM-1 | x-ray diffraction | A | ZN, BCN | 1 (best 0.55) |
| 5N5G | Crystal structure of di-zinc metallo-beta-lactamase vim-1 | x-ray diffraction | A | ZN, BCN | — |
| 5N5H | Crystal structure of metallo-beta-lactamase VIM-1 in complex with ML302F inhibitor | x-ray diffraction | A | ZN, S3C | 1 (best 0.58) |
| 5N5H | Crystal structure of metallo-beta-lactamase vim-1 in complex with ML302F inhibitor | x-ray diffraction | A | ZN, S3C | — |
| 5N5I | Crystal Structure of VIM-1 metallo-beta-lactamase in complex with hydrolysed meropenem | x-ray diffraction | A | ZN, LMP | 1 (best 0.53) |
| 5N5I | Crystal structure of vim-1 metallo-beta-lactamase in complex with hydrolysed meropenem | x-ray diffraction | A | ZN, LMP | — |
| 7AFY | Crystal structure of the metallo-beta-lactamase VIM1 with 1306 | x-ray diffraction | A | RBW, NA, ZN | 1 (best 0.53) |
| 7AFY | Crystal structure of the metallo-beta-lactamase VIM1 with 1306 | x-ray diffraction | A | RBW, NA, ZN | — |
| 7AYJ | Metallo beta-lactamse Vim-1 with a sulfamoyl inhibitor. | x-ray diffraction | A | ZN, S9N | 1 (best 0.51) |
| 7AYJ | Metallo beta-lactamse vim-1 with a sulfamoyl inhibitor. | x-ray diffraction | A | ZN, S9N | — |
| 7UP2 | NDM1-inhibitor co-structure | x-ray diffraction | A | ZN, NZR | 1 (best 0.52) |
| 7UYA | Inhibitor bound VIM1 | x-ray diffraction | A | ZN, OKC | 1 (best 0.51) |
| 7UYB | Inhibitor bound VIM1 | x-ray diffraction | A | ZN, OK0 | 1 (best 0.52) |
| 7UYC | Inhibitor bound VIM1 | x-ray diffraction | A | MG, ZN, OJR | 1 (best 0.54) |
| 8P8Y | Crystal structure of the metallo-beta-lactamase VIM1 with 1657 | x-ray diffraction | A | ZN, X78 | 1 (best 0.51) |
| 8P8Z | Crystal structure of the metallo-beta-lactamase VIM1 with 1963 | x-ray diffraction | A | ZN, X6U | 1 (best 0.51) |
| 8P92 | Crystal structure of the metallo-beta-lactamase VIM1 with 2117 | x-ray diffraction | A | ZN, XB0 | 1 (best 0.53) |
| 8P93 | Crystal structure of the metallo-beta-lactamase VIM1 with 2163 | x-ray diffraction | A | ZN, XAQ | 1 (best 0.52) |
| 8P95 | Crystal structure of the metallo-beta-lactamase VIM1 with 2407 | x-ray diffraction | A | ZN, XA9 | 1 (best 0.52) |
| 8P9P | Crystal structure of the metallo-beta-lactamase VIM1 with 2408 | x-ray diffraction | A | ZN, XB4 | 1 (best 0.53) |
| 8P9Q | Crystal structure of the metallo-beta-lactamase VIM1 with 2455 | x-ray diffraction | A | ZN, XC6 | 1 (best 0.53) |
| 8P9S | Crystal structure of the metallo-beta-lactamase VIM1 with 2482 | x-ray diffraction | A | ZN, XCB | 1 (best 0.51) |
| 8P9T | Crystal structure of the metallo-beta-lactamase VIM1 with 2483 | x-ray diffraction | A | ZN, XCQ | 1 (best 0.52) |
| 8PA3 | Crystal structure of the metallo-beta-lactamase VIM1 with 2500 | x-ray diffraction | A | ZN, XNT | 1 (best 0.52) |
| 8PA4 | Crystal structure of the metallo-beta-lactamase VIM1 with 2526 | x-ray diffraction | A | ZN, XN6 | 1 (best 0.50) |
| 8PA5 | Crystal structure of the metallo-beta-lactamase VIM1 with 2540 | x-ray diffraction | A | ZN, XMZ | 1 (best 0.54) |
| 8PA7 | Crystal structure of the metallo-beta-lactamase VIM1 with 2546 | x-ray diffraction | A | ZN, XMN | 1 (best 0.50) |
| 8PA8 | Crystal structure of the metallo-beta-lactamase VIM1 with 2551 | x-ray diffraction | A | ZN, XLZ | 1 (best 0.52) |
| 8PAA | Crystal structure of the metallo-beta-lactamase VIM1 with 2552 | x-ray diffraction | A | ZN, XO0 | 1 (best 0.57) |
| 8PAC | Crystal structure of the metallo-beta-lactamase VIM1 with 2553 | x-ray diffraction | A | ZN, XNE | 1 (best 0.51) |
| 8PAD | Crystal structure of the metallo-beta-lactamase VIM1 with 2555 | x-ray diffraction | A | ZN, XMU | 1 (best 0.50) |
| 8PAH | Crystal structure of the metallo-beta-lactamase VIM1 with 2596 | x-ray diffraction | A | ZN, XM8 | 1 (best 0.51) |
| 8PAL | Crystal structure of the metallo-beta-lactamase VIM1 with 2651 | x-ray diffraction | A | ZN, XM8 | 1 (best 0.51) |
| 8PAM | Crystal structure of the metallo-beta-lactamase VIM1 with 2652 | x-ray diffraction | A | ZN, XZR | 1 (best 0.51) |
| 8PAN | Crystal structure of the metallo-beta-lactamase VIM1 with 2653 | x-ray diffraction | A | ZN, XZL | 1 (best 0.51) |
| 8PAO | Crystal structure of the metallo-beta-lactamase VIM1 with 2654 | x-ray diffraction | A | ZN, XZH | 1 (best 0.51) |
| 8PB0 | Crystal structure of the metallo-beta-lactamase VIM1 with 2696 | x-ray diffraction | A | ZN, XQE | 1 (best 0.52) |
| 8PB2 | Crystal structure of the metallo-beta-lactamase VIM1 with 2697 | x-ray diffraction | A | ZN, XQ5 | 1 (best 0.51) |
| 8PG2 | Crystal structure of the metallo-beta-lactamase VIM1 with 2728 | x-ray diffraction | A | ZN, YLH | 1 (best 0.51) |
| 8PG3 | Crystal structure of the metallo-beta-lactamase VIM1 with 2729 | x-ray diffraction | A | ZN, YL9 | 1 (best 0.50) |
| 8PG4 | Crystal structure of the metallo-beta-lactamase VIM1 with 2730 | x-ray diffraction | A | ZN, YTO | 1 (best 0.53) |
| 8PG5 | Crystal structure of the metallo-beta-lactamase VIM1 with 2731 | x-ray diffraction | A | ZN, YR8 | 1 (best 0.51) |
| 8PG7 | Crystal structure of the metallo-beta-lactamase VIM1 with 2755 | x-ray diffraction | A | ZN, YV3 | 1 (best 0.52) |
| 8PG9 | Crystal structure of the metallo-beta-lactamase VIM1 with 2817 | x-ray diffraction | A | ZN, YV8 | 1 (best 0.52) |
| 8PGA | Crystal structure of the metallo-beta-lactamase VIM1 with 2818 | x-ray diffraction | A | ZN, YLH | 1 (best 0.53) |
| 8PGB | Crystal structure of the metallo-beta-lactamase VIM1 with 2850 | x-ray diffraction | A | ZN, YSK | 1 (best 0.52) |
| 8PGE | Crystal structure of the metallo-beta-lactamase VIM1 with 2936 | x-ray diffraction | A | ZN, YU8 | 1 (best 0.50) |
| 8PGF | Crystal structure of the metallo-beta-lactamase VIM1 with 2941 | x-ray diffraction | A | ZN, XMU | 1 (best 0.56) |
| 8PGG | Crystal structure of the metallo-beta-lactamase VIM1 with 2954 | x-ray diffraction | A | ZN, YU3 | 1 (best 0.51) |
| 8PGH | Crystal structure of the metallo-beta-lactamase VIM1 with 2955 | x-ray diffraction | A | ZN, YUZ | 1 (best 0.52) |
| 8PGI | Crystal structure of the metallo-beta-lactamase VIM1 with 2984 | x-ray diffraction | A | ZN, YRX | 1 (best 0.49) |
| 8PGJ | Crystal structure of the metallo-beta-lactamase VIM1 with 2985 | x-ray diffraction | A | ZN, YMB | 1 (best 0.49) |
| 8PGK | Crystal structure of the metallo-beta-lactamase VIM1 with 3016 | x-ray diffraction | A | ZN, YVH | 1 (best 0.51) |
| 8PGL | Crystal structure of the metallo-beta-lactamase VIM1 with 3027 | x-ray diffraction | A | ZN, YK5 | 1 (best 0.50) |
| 8PGM | Crystal structure of the metallo-beta-lactamase VIM1 with 3062 | x-ray diffraction | A | ZN, YU0 | 1 (best 0.49) |
| 8PGN | Crystal structure of the metallo-beta-lactamase VIM1 with 3169 | x-ray diffraction | A | ZN, YRF | 1 (best 0.52) |
| 8PGO | Crystal structure of the metallo-beta-lactamase VIM1 with 3183 | x-ray diffraction | A | ZN, YUQ | 1 (best 0.50) |
| 8PGP | Crystal structure of the metallo-beta-lactamase VIM1 with 3193 | x-ray diffraction | A | ZN, YSR | 1 (best 0.53) |
| 8PGQ | Crystal structure of the metallo-beta-lactamase VIM1 with 3225 | x-ray diffraction | A | ZN, YUC | 1 (best 0.51) |
| 8PGR | Crystal structure of the metallo-beta-lactamase VIM1 with 3270 | x-ray diffraction | A | ZN, YJZ | 1 (best 0.50) |
11 records more on the page itself.
Ligands
- ZN · Zinc ion · in 71 records
- BCN · Bicine · in 2 records
- LMP · (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid · in 2 records
- NA · Sodium ion · in 2 records
- RBW · 3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 2 records
- S3C · (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid · in 2 records
- S9N · 3-(4-fluorophenyl)-1-sulfamoyl-pyrrole-2-carboxylic acid · in 2 records
- XM8 · 7-[(1~{S})-1-[[4-(aminomethyl)phenyl]methoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 2 records
- XMU · 7-[(1~{S})-1-[[4-(aminomethyl)phenyl]carbonylamino]ethyl]-3-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1~{H}-indole-2-carboxylic acid · in 2 records
- YLH · 7-[(1~{S})-1-[5-(3-azanylpropyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 2 records
- MG · Magnesium ion · in 1 record
- NZR · (2M)-4'-methyl-2-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide · in 1 record
- OJR · (2P)-4'-(piperidin-4-yl)-4-[(piperidin-4-yl)methyl]-2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide · in 1 record
- OK0 · (2M)-4'-(piperidin-4-yl)-2-(1H-tetrazol-5-yl)-4-(trifluoromethyl)[1,1'-biphenyl]-3-sulfonamide · in 1 record
- OKC · (2M)-4'-(piperidin-4-yl)-2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide · in 1 record
- X6U · 3-[3-cyano-4-(methylsulfonylmethyl)phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- X78 · 3-(2-acetamido-1,3-benzothiazol-7-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XA9 · 3-(2-ethoxypyridin-3-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XAQ · 3-[3-fluoranyl-4-[(piperidin-4-ylsulfonylamino)methyl]phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XB0 · 3-[(1~{S})-1-phenylethoxy]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XB4 · 3-(2-ethoxy-5-fluoranyl-pyridin-3-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XC6 · 7-[(1~{S})-1-acetyloxyethyl]-3-[3-fluoranyl-4-(sulfamoylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 1 record
- XCB · 7-[(1~{S})-1-[4-(aminomethyl)phenyl]carbonyloxyethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 1 record
- XCQ · 7-[(1~{S})-1-(4-azanylbutanoyloxy)ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 1 record
- XLZ · 7-[(1~{S})-1-[4-(3-azanylpropyl)-1,2,3-triazol-1-yl]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 1 record
- XMN · 3-[4-[[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]methyl]-3-fluoranyl-phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XMZ · 3-(3-ethoxy-5-methyl-pyridin-4-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XN6 · 3-[4-(carbamimidamidomethyl)-3-fluoranyl-phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid · in 1 record
- XNE · 7-[(1~{S})-1-[4-(aminomethyl)phenyl]carbonyloxyethyl]-3-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1~{H}-indole-2-carboxylic acid · in 1 record
- XNT · 7-[(1~{S})-1-[4-(2-azanylethyl)phenoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.