UniProt Q9X1X0
Nuclease SbcCD subunit D (Q9X1X0)
Nuclease SbcCD subunit D (UniProt Q9X1X0): 28 experimental structures on GenesisL1, 5 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9X1X0
- Protein
- Nuclease SbcCD subunit D
- Experimental structures
- 28
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 18 · 3 records with a druggable one
Structures
28 records of Q9X1X0 in the MolNFT archive: 28 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Q8U | Crystal structure of MRE11 from thermotoga maritima MSB8 (TM1635) at 2.20 a resolution | x-ray diffraction | A, B | — | — |
| 2Q8U | Crystal structure of MRE11 from thermotoga maritima MSB8 (TM1635) at 2.20 a resolution | x-ray diffraction | A, B | — | — |
| 3QF7 | The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair | x-ray diffraction | D, C | — | — |
| 3QF7 | The MRE11:RAD50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair | x-ray diffraction | D, C | — | — |
| 3QG5 | The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair | x-ray diffraction | C, D | — | — |
| 3QG5 | The MRE11:RAD50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair | x-ray diffraction | C, D | — | — |
| 3THN | Crystal structure of Mre11 core with manganese | x-ray diffraction | A | — | — |
| 3THN | Crystal structure of MRE11 core with manganese | x-ray diffraction | A | — | — |
| 3THO | Crystal structure of Mre11:Rad50 in its ATP/ADP bound state | x-ray diffraction | B | — | — |
| 3THO | Crystal structure of MRE11:RAD50 in its ATP/ADP bound state | x-ray diffraction | B | — | — |
| 4NZV | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | x-ray diffraction | A, B | — | — |
| 4NZV | DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities | x-ray diffraction | A, B | — | — |
| 4O24 | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | x-ray diffraction | A, B | — | — |
| 4O24 | DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities | x-ray diffraction | A, B | — | — |
| 4O43 | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | x-ray diffraction | A, B | — | — |
| 4O43 | DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities | x-ray diffraction | A, B | — | — |
| 4O4K | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | x-ray diffraction | A, B | — | — |
| 4O4K | DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities | x-ray diffraction | A, B | — | — |
| 4O5G | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | x-ray diffraction | A, B | — | — |
| 4O5G | DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities | x-ray diffraction | A, B | — | — |
| 4W9M | AMPPNP bound Rad50 in complex with dsDNA | x-ray diffraction | D, F, J, L | — | — |
| 4W9M | Amppnp bound RAD50 in complex with dsdna | x-ray diffraction | D, F, J, L | — | — |
| 6ASC | Mre11 dimer in complex with Endonuclease inhibitor PFM04 | x-ray diffraction | A, B | MN, BU7 | 6 (best 0.77) |
| 6ASC | MRE11 dimer in complex with endonuclease inhibitor PFM04 | x-ray diffraction | A, B | MN, BU7 | — |
| 6X1Y | Mre11 dimer in complex with small molecule modulator PFMI | x-ray diffraction | A, B | UKV | 6 (best 0.74) |
| 6X1Y | MRE11 dimer in complex with small molecule modulator pfmi | x-ray diffraction | A, B | UKV | — |
| 6X1Z | Mre11 dimer in complex with small molecule modulator PFMJ | x-ray diffraction | A, B | UL1, MG | 6 (best 0.77) |
| 6X1Z | MRE11 dimer in complex with small molecule modulator pfmj | x-ray diffraction | A, B | UL1, MG | — |
Ligands
- BU7 · (5E)-3-butyl-5-[(4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one · in 2 records
- MG · Magnesium ion · in 2 records
- MN · Manganese (II) ion · in 2 records
- UKV · (5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one · in 2 records
- UL1 · (5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one · in 2 records
Elsewhere
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