UniProt Q9UPC5
Probable G-protein coupled receptor 34 (Q9UPC5)
Probable G-protein coupled receptor 34 (UniProt Q9UPC5): 8 experimental structures on GenesisL1, 9 ligands bound, 35 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9UPC5
- Protein
- Probable G-protein coupled receptor 34
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 35 · 7 records with a druggable one
Structures
8 records of Q9UPC5 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8IYX | Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365 | electron microscopy | C | S6R | 4 (best 0.79) |
| 8IZ4 | Lysophosphatidylserine receptor GPR34-Gi complex | electron microscopy | R | TJR, SER, CLR | 5 (best 0.79) |
| 8K4N | Structure of GPR34-Gi complex | electron microscopy | D | VF0 | 5 (best 0.82) |
| 8SAI | Cryo-EM structure of GPR34-Gi complex | electron microscopy | A | S12 | 7 (best 0.82) |
| 8WRB | Lysophosphatidylserine receptor GPR34-Gi complex | electron microscopy | R | CLR, SER, UBL | 5 (best 0.79) |
| 8XBE | Human GPR34 -Gi complex bound to S3E-LysoPS | electron microscopy | A | KW0 | 5 (best 0.80) |
| 8XBH | Human GPR34 -Gi complex bound to M1 | electron microscopy | R | KW3 | 4 (best 0.82) |
| Q9UPC5 | AlphaFold monomer V2.0 prediction for probable G-protein coupled receptor 34 (Q9UPC5) | — | — | — |
Ligands
- CLR · Cholesterol · in 2 records
- SER · Serine · in 2 records
- KW0 · (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[(~{Z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid · in 1 record
- KW3 · (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid · in 1 record
- S12 · O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine · in 1 record
- S6R · 1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid · in 1 record
- TJR · [(2~{R})-2-oxidanyl-3-phosphonooxy-propyl] octadecanoate · in 1 record
- UBL · [(2R)-2-oxidanyl-3-phosphonooxy-propyl] (Z)-octadec-9-enoate · in 1 record
- VF0 · (2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic acid · in 1 record
Elsewhere
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