UniProt Q9UNQ2
Probable dimethyladenosine transferase (Q9UNQ2)
Probable dimethyladenosine transferase (UniProt Q9UNQ2), EC 2.1.1.183: 8 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UNQ2
- Protein
- Probable dimethyladenosine transferase
- EC
- 2.1.1.183
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 15 · 4 records with a druggable one
Structures
9 records of Q9UNQ2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZQ9 | Crystal structure of human Dimethyladenosine transferase | x-ray diffraction | A, B | — | — |
| 1ZQ9 | Crystal structure of human dimethyladenosine transferase | x-ray diffraction | A, B | — | — |
| 6W6C | Structural and catalytic roles of human 18S rRNA methyltransferases DIMT1 in ribosome assembly and… | x-ray diffraction | A, B | — | 6 (best 0.66) |
| 6W6C | Structural and catalytic roles of human 18S rRNA methyltransferases DIMT1 in ribosome assembly and… | x-ray diffraction | A, B | — | — |
| 6W6F | Structural and catalytic roles of human 18S rRNA methyltransferases DIMT1 in ribosome assembly and… | x-ray diffraction | A, B | — | 6 (best 0.59) |
| 6W6F | Structural and catalytic roles of human 18S rRNA methyltransferases DIMT1 in ribosome assembly and… | x-ray diffraction | A, B | — | — |
| 7MQA | Cryo-EM structure of the human SSU processome, state post-A1 | electron microscopy | NL | — | 1 (best 0.86) |
| 7WTS | Cryo-EM structure of a human pre-40S ribosomal subunit - State UTP14 | electron microscopy | 3 | — | 2 (best 0.80) |
| Q9UNQ2 | AlphaFold monomer V2.0 prediction for probable dimethyladenosine transferase (Q9UNQ2) | predicted | A | — | — |
Experiment against prediction
- 1ZQ9 chain B against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.68 Å
- 1ZQ9 chain B against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.68 Å
- 6W6F chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.91 Å
- 6W6F chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.91 Å
- 6W6C chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.92 Å
- 6W6C chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.92 Å
- 1ZQ9 chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.86 Å
- 1ZQ9 chain A against the predicted model Q9UNQ2: TM-score 0.98, RMSD 0.86 Å
- 7WTS chain 3 against the predicted model Q9UNQ2: TM-score 0.97, RMSD 1.02 Å
- 7MQA chain NL against the predicted model Q9UNQ2: TM-score 0.93, RMSD 1.73 Å
Elsewhere
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